Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Auditory environmental enrichment prevents anxiety-like behavior, but not cortisol responses, evoked by 24-h social isolation in zebrafish. / Marchetto, Letícia; Barcellos, Leonardo J. G.; Koakoski, Gessi; Soares, Suelen M.; Pompermaier, Aline; Maffi, Victoria C; Costa, Roberta; da Silva, Carolina G.; Zorzi, Natalie R.; Demin, Konstantin A; Kalueff, Allan V.; de Alcantara Barcellos, Heloisa H.
в: Behavioural Brain Research, Том 404, 113169, 23.04.2021, стр. 113169.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Auditory environmental enrichment prevents anxiety-like behavior, but not cortisol responses, evoked by 24-h social isolation in zebrafish
AU - Marchetto, Letícia
AU - Barcellos, Leonardo J. G.
AU - Koakoski, Gessi
AU - Soares, Suelen M.
AU - Pompermaier, Aline
AU - Maffi, Victoria C
AU - Costa, Roberta
AU - da Silva, Carolina G.
AU - Zorzi, Natalie R.
AU - Demin, Konstantin A
AU - Kalueff, Allan V.
AU - de Alcantara Barcellos, Heloisa H
N1 - Publisher Copyright: © 2021 Elsevier B.V.
PY - 2021/4/23
Y1 - 2021/4/23
N2 - The zebrafish (Danio rerio) is widely used as a promising translational model organism for studying various brain disorders. Zebrafish are also commonly used in behavioral and drug screening assays utilizing individually tested (socially isolated) fish. Various sounds emerge as important exogenous factors that may affect fish behavior. Mounting evidence shows that musical/auditory environmental enrichment can improve welfare of laboratory animals, including fishes. Here, we show that auditory environmental enrichment mitigates anxiogenic-like effects caused by acute social isolation in adult zebrafish. Thus, auditory environmental enrichment may offer an inexpensive, feasible and simple tool to improve welfare of zebrafish stocks in laboratory facilities, reduce unwanted procedural stress, lower non-specific behavioral variance and, hence, collectively improve zebrafish data reliability and reproducibility.
AB - The zebrafish (Danio rerio) is widely used as a promising translational model organism for studying various brain disorders. Zebrafish are also commonly used in behavioral and drug screening assays utilizing individually tested (socially isolated) fish. Various sounds emerge as important exogenous factors that may affect fish behavior. Mounting evidence shows that musical/auditory environmental enrichment can improve welfare of laboratory animals, including fishes. Here, we show that auditory environmental enrichment mitigates anxiogenic-like effects caused by acute social isolation in adult zebrafish. Thus, auditory environmental enrichment may offer an inexpensive, feasible and simple tool to improve welfare of zebrafish stocks in laboratory facilities, reduce unwanted procedural stress, lower non-specific behavioral variance and, hence, collectively improve zebrafish data reliability and reproducibility.
KW - Anxiety-like behavior
KW - Auditory environmental enrichment
KW - Refinement
KW - Social behavior
KW - Stress
KW - Zebrafish
KW - DISORDERS
KW - MUSIC-THERAPY
KW - ANIMAL-MODELS
KW - GENERATION
KW - NEUROSCIENCE RESEARCH
KW - STRESS
KW - BENEFITS
KW - BRAIN
KW - EXPOSURE
UR - http://www.scopus.com/inward/record.url?scp=85101418595&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/373fc9da-b938-36c4-9368-abf26ab1d03b/
U2 - 10.1016/j.bbr.2021.113169
DO - 10.1016/j.bbr.2021.113169
M3 - Article
C2 - 33577884
VL - 404
SP - 113169
JO - Behavioural Brain Research
JF - Behavioural Brain Research
SN - 0166-4328
M1 - 113169
ER -
ID: 74174429