TY - JOUR

T1 - Apoptotic death of F9 embryonal carcinoma cells is cell density-dependent

AU - Malashicheva, A. B.

AU - Kislyakova, T. V.

AU - Pospelov, V. A.

PY - 1998/1/1

Y1 - 1998/1/1

N2 - Apoptosis, or programmed cell death, is an active process fundamental to the development and homeostasis of multicellular organisms. Mouse embryonal carcinoma F9 cell line was shown to express wild type p53 protein known to be one of the major regulators of apoptotic cell death. Herein we describe apoptosis-inducing conditions for F9 cells. The density reached by a cell population in culture is shown to be a factor of apoptotic death for both undifferentiated and induced to differentiation F9 cells. However, the relationships between population cell density and apoptosis induction are different in undifferentiated and differentiating cells.

AB - Apoptosis, or programmed cell death, is an active process fundamental to the development and homeostasis of multicellular organisms. Mouse embryonal carcinoma F9 cell line was shown to express wild type p53 protein known to be one of the major regulators of apoptotic cell death. Herein we describe apoptosis-inducing conditions for F9 cells. The density reached by a cell population in culture is shown to be a factor of apoptotic death for both undifferentiated and induced to differentiation F9 cells. However, the relationships between population cell density and apoptosis induction are different in undifferentiated and differentiating cells.

UR - http://www.scopus.com/inward/record.url?scp=1542531641&partnerID=8YFLogxK

M3 - статья

C2 - 9541970

AN - SCOPUS:1542531641

VL - 40

SP - 21

EP - 22

JO - Цитология

JF - Цитология

SN - 0041-3771

IS - 1

ER -