Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
A full atom-economical domino method has been developed for the preparation of alkyl 5-amino-4-cyano-1H-pyrrole-2-carboxylates by transannulation of 5-alkoxyisoxazoles with malononitrile under Fe(ii) catalysis. Alkyl 5-amino-4-cyano-1H-pyrrole-2-carboxylates are excellent building blocks for various annulation reactions, leading to new derivatives of 1H-pyrrolo[1,2-a]imidazole and pyrrolo[2,3-d]pyrimidine. The DFT calculations of mechanistic details of alkyl 5-amino-4-cyano-1H-pyrrole-2-carboxylate formation are presented.
Язык оригинала | английский |
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Страницы (с-по) | 1976-1984 |
Число страниц | 9 |
Журнал | Organic and Biomolecular Chemistry |
Том | 19 |
Номер выпуска | 9 |
DOI | |
Состояние | Опубликовано - 7 мар 2021 |
ID: 75289470