TY - JOUR

T1 - A.E.Favorskii's scientific legacy in modern organic chemistry

T2 - Prototropic acetylene - Allene isomerization and the acetylene zipper reaction

AU - Danilkina, Natalia A.

AU - Vasileva, Anna A.

AU - Balova, Irina A.

PY - 2020/1/31

Y1 - 2020/1/31

N2 - Aleksei Evgrafovich Favorskii was an outstanding organic chemist who left a great scientific legacy as a result of his long and fruitful research. Most of theoretically and practically important discoveries made by A.E.Favorskii lay in the area of acetylene chemistry. Nowadays the reactions he discovered, namely, acetylene--allene isomerization, Favorskii reaction, retro-Favorskii reaction, Favorskii rearrangement and vinylation are widely used in industry and in laboratory organic synthesis. This review summarizes the key scientific achievements of A.E.Favorskii and describes further development of these areas in modern organic synthesis. Detailed consideration is given for the acetylene--allene isomerization and `acetylene zipper' reaction as convenient synthetic tools for the synthesis of methyl-substituted acetylenes and acetylenes with a terminal triple bond, respectively. The review presents examples of the use of these reactions in the modern organic synthesis of complex molecules, including natural co

AB - Aleksei Evgrafovich Favorskii was an outstanding organic chemist who left a great scientific legacy as a result of his long and fruitful research. Most of theoretically and practically important discoveries made by A.E.Favorskii lay in the area of acetylene chemistry. Nowadays the reactions he discovered, namely, acetylene--allene isomerization, Favorskii reaction, retro-Favorskii reaction, Favorskii rearrangement and vinylation are widely used in industry and in laboratory organic synthesis. This review summarizes the key scientific achievements of A.E.Favorskii and describes further development of these areas in modern organic synthesis. Detailed consideration is given for the acetylene--allene isomerization and `acetylene zipper' reaction as convenient synthetic tools for the synthesis of methyl-substituted acetylenes and acetylenes with a terminal triple bond, respectively. The review presents examples of the use of these reactions in the modern organic synthesis of complex molecules, including natural co

KW - acetylene

KW - acetylene-allene

KW - acetylenic

KW - acid

KW - alcohol

KW - amide

KW - amine

KW - carboxylic

KW - chemistry

KW - Favorskii

KW - isomerization

KW - ketone

KW - methylacetylene

KW - N-heterocycle

KW - organic

KW - Prototropic

KW - reaction

KW - rearrangement

KW - Vinylation

KW - Zipper

KW - Алексей Евграфович

KW - ацетилен

KW - ацетилен-алленовая

KW - ацетиленовая молния

KW - винилирование

KW - изомеризация

KW - кетон

KW - перегруппировка

KW - реакция

KW - спирт

KW - Фаворский

KW - Фаворского

KW - химия

KW - эфир

KW - acetylene

KW - acetylene-allene

KW - acetylenic

KW - acid

KW - alcohol

KW - amide

KW - amine

KW - carboxylic

KW - chemistry

KW - Favorskii

KW - isomerization

KW - ketone

KW - methylacetylene

KW - N-heterocycle

KW - organic

KW - Prototropic

KW - reaction

KW - rearrangement

KW - Vinylation

KW - Zipper

KW - Алексей Евграфович

KW - ацетилен

KW - ацетилен-алленовая

KW - ацетиленовая молния

KW - винилирование

KW - изомеризация

KW - кетон

KW - перегруппировка

KW - реакция

KW - спирт

KW - Фаворский

KW - Фаворского

KW - химия

KW - эфир

UR - http://www.scopus.com/inward/record.url?scp=85081407833&partnerID=8YFLogxK

U2 - 10.1070/RCR4902

DO - 10.1070/RCR4902

M3 - Review article

AN - SCOPUS:85081407833

VL - 89

SP - 125

EP - 171

JO - Russian Chemical Reviews

JF - Russian Chemical Reviews

SN - 0036-021X

IS - 1

ER -