Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles. / Lukin, Alexei; Bakholdina, Anna; Kryukova, Anna; Sapegin, Alexander; Krasavin, Mikhail.
в: Beilstein Journal of Organic Chemistry, Том 15, 01.01.2019, стр. 1061-1064.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles
AU - Lukin, Alexei
AU - Bakholdina, Anna
AU - Kryukova, Anna
AU - Sapegin, Alexander
AU - Krasavin, Mikhail
PY - 2019/1/1
Y1 - 2019/1/1
N2 - A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported basepromoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.
AB - A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported basepromoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.
KW - Alkyne hydroamination
KW - Cyclocondensation
KW - Lewis acid catalysis
KW - Multicomponent reactions
KW - Propargylurea
UR - http://www.scopus.com/inward/record.url?scp=85066508362&partnerID=8YFLogxK
U2 - 10.3762/bjoc.15.103
DO - 10.3762/bjoc.15.103
M3 - Article
VL - 15
SP - 1061
EP - 1064
JO - Beilstein Journal of Organic Chemistry
JF - Beilstein Journal of Organic Chemistry
SN - 1860-5397
ER -
ID: 42472727