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A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles. / Lukin, Alexei; Bakholdina, Anna; Kryukova, Anna; Sapegin, Alexander; Krasavin, Mikhail.

в: Beilstein Journal of Organic Chemistry, Том 15, 01.01.2019, стр. 1061-1064.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Lukin, Alexei ; Bakholdina, Anna ; Kryukova, Anna ; Sapegin, Alexander ; Krasavin, Mikhail. / A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles. в: Beilstein Journal of Organic Chemistry. 2019 ; Том 15. стр. 1061-1064.

BibTeX

@article{ed2ccc6c2681479a9e4eb64992b2edea,
title = "A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles",
abstract = "A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported basepromoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.",
keywords = "Alkyne hydroamination, Cyclocondensation, Lewis acid catalysis, Multicomponent reactions, Propargylurea",
author = "Alexei Lukin and Anna Bakholdina and Anna Kryukova and Alexander Sapegin and Mikhail Krasavin",
year = "2019",
month = jan,
day = "1",
doi = "10.3762/bjoc.15.103",
language = "English",
volume = "15",
pages = "1061--1064",
journal = "Beilstein Journal of Organic Chemistry",
issn = "1860-5397",
publisher = "Beilstein-Institut Zur Forderung der Chemischen Wissenschaften",

}

RIS

TY - JOUR

T1 - A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles

AU - Lukin, Alexei

AU - Bakholdina, Anna

AU - Kryukova, Anna

AU - Sapegin, Alexander

AU - Krasavin, Mikhail

PY - 2019/1/1

Y1 - 2019/1/1

N2 - A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported basepromoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.

AB - A three-component reaction involving in situ generation of propargylureas and subsequent Zn(OTf)2-mediated cyclocondensation with a primary amine yielded trisubstituted 2-aminoimidazoles. These findings are in contrast to the previously reported basepromoted unimolecular cyclization of propargylureas (leading to 2-imidazolones) and extend the range of Lewis acid-catalyzed azole syntheses based on N-carbonyl propargylamines.

KW - Alkyne hydroamination

KW - Cyclocondensation

KW - Lewis acid catalysis

KW - Multicomponent reactions

KW - Propargylurea

UR - http://www.scopus.com/inward/record.url?scp=85066508362&partnerID=8YFLogxK

U2 - 10.3762/bjoc.15.103

DO - 10.3762/bjoc.15.103

M3 - Article

VL - 15

SP - 1061

EP - 1064

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

SN - 1860-5397

ER -

ID: 42472727