TY - JOUR

T1 - A study on the dilational modulus of adsorbed globular protein films – Under a near periodic area fluctuation and rapid surface perturbation

AU - Rivas, Johann Eduardo Maradiaga

AU - Hussain, Siam

AU - Tseng, Wen-Chi

AU - Носков, Борис Анатольевич

AU - Lin, Shi-Yow

PY - 2024/2/1

Y1 - 2024/2/1

N2 - Background: Understanding how surface area (SA) fluctuation affects the dilational modulus (E) of globular protein films is crucial for evaluating their mechanical properties and practical utility. However, limited reports are available in the literature and the measurement error is unclear. Method: The impact of SA fluctuation and large, forced perturbation on the E of bovine serum albumin (BSA) and human serum albumin (HSA) film was investigated. The E was evaluated by analyzing surface tension (ST) and SA relaxation data obtained using a pendant bubble tensiometer. Significant findings: The data revealed that a large fluctuation in SA exerted a notable influence on the E: a distinct peak and minima in E being detected at the onset and end, respectively (at magnitude ΔA/A > ∼3 % and at oscillation frequency ƒ = 0.3 – 1.1 mHz for adsorbed BSA/HSA film). In contrast, a comparatively smaller SA fluctuation caused only a slight variation in E. Furthermore, a large, forced perturbation led to a rise in E, exhibiting a distinctly high value after a rapid bubble compression, followed by a subsequent decrease to a distinctly low E.

AB - Background: Understanding how surface area (SA) fluctuation affects the dilational modulus (E) of globular protein films is crucial for evaluating their mechanical properties and practical utility. However, limited reports are available in the literature and the measurement error is unclear. Method: The impact of SA fluctuation and large, forced perturbation on the E of bovine serum albumin (BSA) and human serum albumin (HSA) film was investigated. The E was evaluated by analyzing surface tension (ST) and SA relaxation data obtained using a pendant bubble tensiometer. Significant findings: The data revealed that a large fluctuation in SA exerted a notable influence on the E: a distinct peak and minima in E being detected at the onset and end, respectively (at magnitude ΔA/A > ∼3 % and at oscillation frequency ƒ = 0.3 – 1.1 mHz for adsorbed BSA/HSA film). In contrast, a comparatively smaller SA fluctuation caused only a slight variation in E. Furthermore, a large, forced perturbation led to a rise in E, exhibiting a distinctly high value after a rapid bubble compression, followed by a subsequent decrease to a distinctly low E.

KW - Adsorbed film

KW - Dilational modulus

KW - Globular protein

KW - Pendant bubble tensiometry

KW - Perturbed interface

KW - Surface fluctuation

UR - https://www.mendeley.com/catalogue/15e38a28-be06-38b3-ad57-9c40b5165018/

U2 - 10.1016/j.jtice.2023.105288

DO - 10.1016/j.jtice.2023.105288

M3 - Article

VL - 155

JO - Journal of the Taiwan Institute of Chemical Engineers

JF - Journal of the Taiwan Institute of Chemical Engineers

SN - 1876-1070

M1 - 105288

ER -