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A convenient preparation of diversely substituted fused 2-amino- and 2-alkylthionicotinonitriles under microwave irradiation. / Krasavin, M.; Sapegin, A.; Dorogov, M.

в: Tetrahedron Letters, Том 56, № 1, 2015, стр. 56-60.

Результаты исследований: Научные публикации в периодических изданияхстатья

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Krasavin, M. ; Sapegin, A. ; Dorogov, M. / A convenient preparation of diversely substituted fused 2-amino- and 2-alkylthionicotinonitriles under microwave irradiation. в: Tetrahedron Letters. 2015 ; Том 56, № 1. стр. 56-60.

BibTeX

@article{e4eb981d82d442d281c71fed1c551bba,
title = "A convenient preparation of diversely substituted fused 2-amino- and 2-alkylthionicotinonitriles under microwave irradiation",
abstract = "{\textcopyright} 2014 Elsevier B.V. All rights reserved. We describe a convenient and operationally simple protocol to prepare nicotinonitriles fused to either a cycloalkane or a saturated heterocycle, containing diverse substituents at position 2 of the nicotinonitrile core, under microwave irradiation. The protocol is useful for rapid and automated synthesis of the target compounds. An unusual case of the loss of a tert-butyl group is observed when tert-butylamine was used to bring about the pyridine ring formation.",
author = "M. Krasavin and A. Sapegin and M. Dorogov",
year = "2015",
doi = "10.1016/j.tetlet.2014.09.067",
language = "English",
volume = "56",
pages = "56--60",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - A convenient preparation of diversely substituted fused 2-amino- and 2-alkylthionicotinonitriles under microwave irradiation

AU - Krasavin, M.

AU - Sapegin, A.

AU - Dorogov, M.

PY - 2015

Y1 - 2015

N2 - © 2014 Elsevier B.V. All rights reserved. We describe a convenient and operationally simple protocol to prepare nicotinonitriles fused to either a cycloalkane or a saturated heterocycle, containing diverse substituents at position 2 of the nicotinonitrile core, under microwave irradiation. The protocol is useful for rapid and automated synthesis of the target compounds. An unusual case of the loss of a tert-butyl group is observed when tert-butylamine was used to bring about the pyridine ring formation.

AB - © 2014 Elsevier B.V. All rights reserved. We describe a convenient and operationally simple protocol to prepare nicotinonitriles fused to either a cycloalkane or a saturated heterocycle, containing diverse substituents at position 2 of the nicotinonitrile core, under microwave irradiation. The protocol is useful for rapid and automated synthesis of the target compounds. An unusual case of the loss of a tert-butyl group is observed when tert-butylamine was used to bring about the pyridine ring formation.

U2 - 10.1016/j.tetlet.2014.09.067

DO - 10.1016/j.tetlet.2014.09.067

M3 - Article

VL - 56

SP - 56

EP - 60

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 1

ER -

ID: 3988776