TY - CONF

T1 - 3D-models creation based on solid tumor cell lines for assessment of antitumor treatment.

AU - Prosekina, Elizaveta

AU - Danilova, Anna

PY - 2020

Y1 - 2020

N2 - The creation of three-dimensional cellular models promotes the study of tumor microenvironment. It contributes to a more adequate assessment of the therapeutic effects on malignant cells, which improves the prognostic value of preclinical research and promotes the progress of effective drug therapy for malignant tumors. In this study, 3D models (tumoroids) were obtained from solid tumors cells of patients treated at the N.N. Petrov National Medical Research Center of Oncology. The therapeutic effect of chemotherapy on tumoroids with previous treatment of patients was analyzed.

AB - The creation of three-dimensional cellular models promotes the study of tumor microenvironment. It contributes to a more adequate assessment of the therapeutic effects on malignant cells, which improves the prognostic value of preclinical research and promotes the progress of effective drug therapy for malignant tumors. In this study, 3D models (tumoroids) were obtained from solid tumors cells of patients treated at the N.N. Petrov National Medical Research Center of Oncology. The therapeutic effect of chemotherapy on tumoroids with previous treatment of patients was analyzed.

KW - 3D system

KW - antitumor therapy

KW - solid tumors

KW - tumoroids

KW - 3D system

KW - antitumor therapy

KW - solid tumors

KW - tumoroids

M3 - Abstract

SP - 509

EP - 510

ER -