Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
2 H-Azirines as C-C Annulation Reagents in Cu-Catalyzed Synthesis of Furo[3,2-c]quinolone Derivatives. / Sakharov, Pavel A.; Rostovskii, Nikolai V.; Khlebnikov, Alexander F.; Panikorovskii, Taras L.; Novikov, Mikhail S.
в: Organic Letters, Том 21, № 10, 17.05.2019, стр. 3615-3619.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - 2 H-Azirines as C-C Annulation Reagents in Cu-Catalyzed Synthesis of Furo[3,2-c]quinolone Derivatives
AU - Sakharov, Pavel A.
AU - Rostovskii, Nikolai V.
AU - Khlebnikov, Alexander F.
AU - Panikorovskii, Taras L.
AU - Novikov, Mikhail S.
PY - 2019/5/17
Y1 - 2019/5/17
N2 - A method of furo-annulation of 4-hydroxy-2-oxoquinoline-3-carboxylates with 3-arylazirines under Cu(II) catalysis was developed to synthesize a variety of 2,3-dihydrofuro[3,2-c]quinolones bearing a carbamate group at the C2 position. The reaction involves an azirine ring opening across the N-C2 bond and formation of a dihydrofuran ring with the inclusion of two azirine carbon atoms, accompanied by a shift of the ester group to the nitrogen. The discovered reaction is the first example of the use of 2H-azirines for furo-annulation.
AB - A method of furo-annulation of 4-hydroxy-2-oxoquinoline-3-carboxylates with 3-arylazirines under Cu(II) catalysis was developed to synthesize a variety of 2,3-dihydrofuro[3,2-c]quinolones bearing a carbamate group at the C2 position. The reaction involves an azirine ring opening across the N-C2 bond and formation of a dihydrofuran ring with the inclusion of two azirine carbon atoms, accompanied by a shift of the ester group to the nitrogen. The discovered reaction is the first example of the use of 2H-azirines for furo-annulation.
UR - http://www.scopus.com/inward/record.url?scp=85065847330&partnerID=8YFLogxK
U2 - 10.1021/acs.orglett.9b01043
DO - 10.1021/acs.orglett.9b01043
M3 - Article
C2 - 31063384
AN - SCOPUS:85065847330
VL - 21
SP - 3615
EP - 3619
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 10
ER -
ID: 42845410