Standard

"2 + 1" Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules. / Gorshkov, N. I.; Schibli, R.; Schubiger, A. P.; Lumpov, A. A.; Miroslavov, A. E.; Suglobov, D. N.

в: Journal of Organometallic Chemistry, Том 689, № 25 SPEC. ISS., 06.12.2004, стр. 4757-4763.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Gorshkov, NI, Schibli, R, Schubiger, AP, Lumpov, AA, Miroslavov, AE & Suglobov, DN 2004, '"2 + 1" Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules', Journal of Organometallic Chemistry, Том. 689, № 25 SPEC. ISS., стр. 4757-4763. https://doi.org/10.1016/j.jorganchem.2004.09.019

APA

Gorshkov, N. I., Schibli, R., Schubiger, A. P., Lumpov, A. A., Miroslavov, A. E., & Suglobov, D. N. (2004). "2 + 1" Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules. Journal of Organometallic Chemistry, 689(25 SPEC. ISS.), 4757-4763. https://doi.org/10.1016/j.jorganchem.2004.09.019

Vancouver

Gorshkov NI, Schibli R, Schubiger AP, Lumpov AA, Miroslavov AE, Suglobov DN. "2 + 1" Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules. Journal of Organometallic Chemistry. 2004 Дек. 6;689(25 SPEC. ISS.):4757-4763. https://doi.org/10.1016/j.jorganchem.2004.09.019

Author

Gorshkov, N. I. ; Schibli, R. ; Schubiger, A. P. ; Lumpov, A. A. ; Miroslavov, A. E. ; Suglobov, D. N. / "2 + 1" Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules. в: Journal of Organometallic Chemistry. 2004 ; Том 689, № 25 SPEC. ISS. стр. 4757-4763.

BibTeX

@article{e2b53cae8e0540299c8765f3dc29c2ae,
title = "{"}2 + 1{"} Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules",
abstract = "{"}2 + 1{"} Dithiocarbamate (DTC)-isocyanide (ISO) system was studied to label amino acids and model peptides with 99mTc(CO)3+ fragment. Two ways were used: (i) conjugation via free carboxy group of bifunctional DTC [S2CNMe2- (L3), S2CNHCH2COO2- (L1) and S 2C(C4H7N)COO2- (L2)] using pre-labeling procedure and (ii) conjugation via isocyanide ligand [tert-BuNC (L4), EtOC(O)CH2NHC(O)CH2NC (L5), and gly-gly-gly-CH 2NHC(O)CH2NC (L6)]. Complexes M(CO)3L2L4 - (1a, 1b), M(CO)3L3L4- (2a, 2b) and bioconjugates M(CO)3L1L5 (5a, 5b), and M(CO)3L1L6 (6b) (a, M = Re; b, 99mTc) were synthesized. Bioconjugates 4a and 4b were prepared by reaction of histidine methyl ester with 2a and 2b, respectively. All rhenium complexes were characterized by 1H and 13C NMR, IR, and MS spectroscopy and complexes with 99mTc, by HPLC using rhenium analogs as references.",
keywords = "Biomolecules, Dithiocarbamates, Isocyanides, Rhenium, Technetium",
author = "Gorshkov, {N. I.} and R. Schibli and Schubiger, {A. P.} and Lumpov, {A. A.} and Miroslavov, {A. E.} and Suglobov, {D. N.}",
note = "Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "2004",
month = dec,
day = "6",
doi = "10.1016/j.jorganchem.2004.09.019",
language = "English",
volume = "689",
pages = "4757--4763",
journal = "Journal of Organometallic Chemistry",
issn = "0022-328X",
publisher = "Elsevier",
number = "25 SPEC. ISS.",

}

RIS

TY - JOUR

T1 - "2 + 1" Dithiocarbamate-isocyanide chelating systems for linking M(CO)3 + (M = 99mTc, Re) fragment to biomolecules

AU - Gorshkov, N. I.

AU - Schibli, R.

AU - Schubiger, A. P.

AU - Lumpov, A. A.

AU - Miroslavov, A. E.

AU - Suglobov, D. N.

N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 2004/12/6

Y1 - 2004/12/6

N2 - "2 + 1" Dithiocarbamate (DTC)-isocyanide (ISO) system was studied to label amino acids and model peptides with 99mTc(CO)3+ fragment. Two ways were used: (i) conjugation via free carboxy group of bifunctional DTC [S2CNMe2- (L3), S2CNHCH2COO2- (L1) and S 2C(C4H7N)COO2- (L2)] using pre-labeling procedure and (ii) conjugation via isocyanide ligand [tert-BuNC (L4), EtOC(O)CH2NHC(O)CH2NC (L5), and gly-gly-gly-CH 2NHC(O)CH2NC (L6)]. Complexes M(CO)3L2L4 - (1a, 1b), M(CO)3L3L4- (2a, 2b) and bioconjugates M(CO)3L1L5 (5a, 5b), and M(CO)3L1L6 (6b) (a, M = Re; b, 99mTc) were synthesized. Bioconjugates 4a and 4b were prepared by reaction of histidine methyl ester with 2a and 2b, respectively. All rhenium complexes were characterized by 1H and 13C NMR, IR, and MS spectroscopy and complexes with 99mTc, by HPLC using rhenium analogs as references.

AB - "2 + 1" Dithiocarbamate (DTC)-isocyanide (ISO) system was studied to label amino acids and model peptides with 99mTc(CO)3+ fragment. Two ways were used: (i) conjugation via free carboxy group of bifunctional DTC [S2CNMe2- (L3), S2CNHCH2COO2- (L1) and S 2C(C4H7N)COO2- (L2)] using pre-labeling procedure and (ii) conjugation via isocyanide ligand [tert-BuNC (L4), EtOC(O)CH2NHC(O)CH2NC (L5), and gly-gly-gly-CH 2NHC(O)CH2NC (L6)]. Complexes M(CO)3L2L4 - (1a, 1b), M(CO)3L3L4- (2a, 2b) and bioconjugates M(CO)3L1L5 (5a, 5b), and M(CO)3L1L6 (6b) (a, M = Re; b, 99mTc) were synthesized. Bioconjugates 4a and 4b were prepared by reaction of histidine methyl ester with 2a and 2b, respectively. All rhenium complexes were characterized by 1H and 13C NMR, IR, and MS spectroscopy and complexes with 99mTc, by HPLC using rhenium analogs as references.

KW - Biomolecules

KW - Dithiocarbamates

KW - Isocyanides

KW - Rhenium

KW - Technetium

UR - http://www.scopus.com/inward/record.url?scp=12144256837&partnerID=8YFLogxK

U2 - 10.1016/j.jorganchem.2004.09.019

DO - 10.1016/j.jorganchem.2004.09.019

M3 - Article

AN - SCOPUS:12144256837

VL - 689

SP - 4757

EP - 4763

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

SN - 0022-328X

IS - 25 SPEC. ISS.

ER -

ID: 76835916