The pandemic of the newly coronavirus infection COVID-19 was the test primarily for scientists, experts in epidemiology, infectiology and other fields of medicine participating in addressing the issues of organization and delivery of care, forming up the whole ideology of public health in new conditions. The lecture presents the complex analysis of development of the epidemiologic process, concerning a review of last epidemics, regional features, forecast and modelling approaches, the observers will be able to evaluate demographic, social and medical aspects of evolution. The emphasis is made on the consequences of the transferred infection that directly affect human health, a brief analysis of the clinical manifestations of post-covid syndrome and its expected impact on people, the functioning of all levels of health care, including rehabilitation. The key role of vaccination as the main method of population immunity, prevention of SARS-CoV-2 infection, the development of severe and complicated forms of the disease, as well as domestic manufacturers and manufacturers of several safe and highly effective vaccines has been determined. The article is intended for a wide range of medical professionals, healthcare organizers, government officials and other interested parties.