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СРАВНЕНИЕ ЧАСТОТ МУТАЦИИ CCR5DEL32 В ГЕНЕ CCR5 У РУССКИХ, ТУВИНЦЕВ, А ТАКЖЕ В ГРУППАХ ВИЧ-ИНФИЦИРОВАННЫХ ИНДИВИДУУМОВ. / Apryatin, S. A.; Rakhmanaliev, E. R.; Nikolaeva, I. A.; Ruban, S. V.; Vazykhova, F. G.; Klimov, E. A.; Sulimova, G. E.; Sidorovich, I. G.

в: ГЕНЕТИКА, Том 41, № 11, 01.12.2005, стр. 1559-1562.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Apryatin, SA, Rakhmanaliev, ER, Nikolaeva, IA, Ruban, SV, Vazykhova, FG, Klimov, EA, Sulimova, GE & Sidorovich, IG 2005, 'СРАВНЕНИЕ ЧАСТОТ МУТАЦИИ CCR5DEL32 В ГЕНЕ CCR5 У РУССКИХ, ТУВИНЦЕВ, А ТАКЖЕ В ГРУППАХ ВИЧ-ИНФИЦИРОВАННЫХ ИНДИВИДУУМОВ', ГЕНЕТИКА, Том. 41, № 11, стр. 1559-1562.

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Author

Apryatin, S. A. ; Rakhmanaliev, E. R. ; Nikolaeva, I. A. ; Ruban, S. V. ; Vazykhova, F. G. ; Klimov, E. A. ; Sulimova, G. E. ; Sidorovich, I. G. / СРАВНЕНИЕ ЧАСТОТ МУТАЦИИ CCR5DEL32 В ГЕНЕ CCR5 У РУССКИХ, ТУВИНЦЕВ, А ТАКЖЕ В ГРУППАХ ВИЧ-ИНФИЦИРОВАННЫХ ИНДИВИДУУМОВ. в: ГЕНЕТИКА. 2005 ; Том 41, № 11. стр. 1559-1562.

BibTeX

@article{80af113f82f4402e9759296858d32e80,
title = "СРАВНЕНИЕ ЧАСТОТ МУТАЦИИ CCR5DEL32 В ГЕНЕ CCR5 У РУССКИХ, ТУВИНЦЕВ, А ТАКЖЕ В ГРУППАХ ВИЧ-ИНФИЦИРОВАННЫХ ИНДИВИДУУМОВ",
abstract = "The 32-bp deletion (CCR5del32 mutation) in the CCR5 (chemokine (C-C motif) receptor 5) gene, encoding CCR5 chemokine receptor, is one of the factors determining natural resistance to human immunodeficiency virus (HIV-1) infection. In the present study, the samples of Russians (n = 107), Tuvinians (n = 50), and HIV-infected individuals were examined for the presence of CCR5del32 mutation in the CCR5 gene. The CCR5del32 allele frequency in Russians and Tuvinians constituted 7.84 and 2%, respectively. Among HIV-1 infected individuals, two groups, of macrophage-tropic HIV-1 strain- and T-cell-tropic HIV-1 strain-infected were distinguished. The CCR5del32 allele frequency in the first group (6.45%) was lower than in the second one (8.73%). Statistical treatment of the HIV-1 infected individuals typing data showed that the difference in the CCR5del32 allele frequencies between the groups of sexually (macrophage-tropic) and parenterally (T-cell-tropic) infected individuals observed was within the limit of random deviation.",
author = "Apryatin, {S. A.} and Rakhmanaliev, {E. R.} and Nikolaeva, {I. A.} and Ruban, {S. V.} and Vazykhova, {F. G.} and Klimov, {E. A.} and Sulimova, {G. E.} and Sidorovich, {I. G.}",
year = "2005",
month = dec,
day = "1",
language = "русский",
volume = "41",
pages = "1559--1562",
journal = "ГЕНЕТИКА",
issn = "0016-6758",
publisher = "Международная книга",
number = "11",

}

RIS

TY - JOUR

T1 - СРАВНЕНИЕ ЧАСТОТ МУТАЦИИ CCR5DEL32 В ГЕНЕ CCR5 У РУССКИХ, ТУВИНЦЕВ, А ТАКЖЕ В ГРУППАХ ВИЧ-ИНФИЦИРОВАННЫХ ИНДИВИДУУМОВ

AU - Apryatin, S. A.

AU - Rakhmanaliev, E. R.

AU - Nikolaeva, I. A.

AU - Ruban, S. V.

AU - Vazykhova, F. G.

AU - Klimov, E. A.

AU - Sulimova, G. E.

AU - Sidorovich, I. G.

PY - 2005/12/1

Y1 - 2005/12/1

N2 - The 32-bp deletion (CCR5del32 mutation) in the CCR5 (chemokine (C-C motif) receptor 5) gene, encoding CCR5 chemokine receptor, is one of the factors determining natural resistance to human immunodeficiency virus (HIV-1) infection. In the present study, the samples of Russians (n = 107), Tuvinians (n = 50), and HIV-infected individuals were examined for the presence of CCR5del32 mutation in the CCR5 gene. The CCR5del32 allele frequency in Russians and Tuvinians constituted 7.84 and 2%, respectively. Among HIV-1 infected individuals, two groups, of macrophage-tropic HIV-1 strain- and T-cell-tropic HIV-1 strain-infected were distinguished. The CCR5del32 allele frequency in the first group (6.45%) was lower than in the second one (8.73%). Statistical treatment of the HIV-1 infected individuals typing data showed that the difference in the CCR5del32 allele frequencies between the groups of sexually (macrophage-tropic) and parenterally (T-cell-tropic) infected individuals observed was within the limit of random deviation.

AB - The 32-bp deletion (CCR5del32 mutation) in the CCR5 (chemokine (C-C motif) receptor 5) gene, encoding CCR5 chemokine receptor, is one of the factors determining natural resistance to human immunodeficiency virus (HIV-1) infection. In the present study, the samples of Russians (n = 107), Tuvinians (n = 50), and HIV-infected individuals were examined for the presence of CCR5del32 mutation in the CCR5 gene. The CCR5del32 allele frequency in Russians and Tuvinians constituted 7.84 and 2%, respectively. Among HIV-1 infected individuals, two groups, of macrophage-tropic HIV-1 strain- and T-cell-tropic HIV-1 strain-infected were distinguished. The CCR5del32 allele frequency in the first group (6.45%) was lower than in the second one (8.73%). Statistical treatment of the HIV-1 infected individuals typing data showed that the difference in the CCR5del32 allele frequencies between the groups of sexually (macrophage-tropic) and parenterally (T-cell-tropic) infected individuals observed was within the limit of random deviation.

UR - http://www.scopus.com/inward/record.url?scp=33644829548&partnerID=8YFLogxK

UR - https://elibrary.ru/item.asp?id=9172892

M3 - статья

C2 - 16358723

AN - SCOPUS:33644829548

VL - 41

SP - 1559

EP - 1562

JO - ГЕНЕТИКА

JF - ГЕНЕТИКА

SN - 0016-6758

IS - 11

ER -

ID: 115018600