Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
К вопросу о дифференциальной диагностике ANCA-позитивного генерализованного саркоидоза и ANCA-ассоциированного полиангиита. / Koval'Skiy, Georgiy B.; Ariel, Boris M.; Volchkov, Vladimir A.; Danilova, Irina A.; Poliyevets, Aleksandra G.
в: ПУЛЬМОНОЛОГИЯ, Том 28, № 4, 2018, стр. 496-502.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - К вопросу о дифференциальной диагностике ANCA-позитивного генерализованного саркоидоза и ANCA-ассоциированного полиангиита
AU - Koval'Skiy, Georgiy B.
AU - Ariel, Boris M.
AU - Volchkov, Vladimir A.
AU - Danilova, Irina A.
AU - Poliyevets, Aleksandra G.
N1 - Publisher Copyright: © 2018 National Research University Higher School of Economics. All rights reserved. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2018
Y1 - 2018
N2 - An autopsy case of a female patient of 65 years old was reported in the article. This case demonstrated clinical and anatomical features of chronic generalized sarcoidosis with predominant lesion of the lungs (extended bilateral fibrosis) and the kidneys (interstitial nephritis with segmental glo-merulosclerosis). Long-term steroid therapy resulted in a significant slowing progression of the disease. This case was characterized by a prominent vasculitis which caused the misdiagnosis of ANCA-associated polyangiitis. Severe anemia and secondary immunodeficiency that were partially drug-induced due to the long-term steroid therapy were other manifestations of this disease. The advanced disease was complicated by lower respiratory tract infection, acute respiratory distress-syndrome, and multiple organ dysfunction that caused the patient's death. A comprehensive pathological investigation including immunohistochemistry had the crucial role for the final diagnosis.
AB - An autopsy case of a female patient of 65 years old was reported in the article. This case demonstrated clinical and anatomical features of chronic generalized sarcoidosis with predominant lesion of the lungs (extended bilateral fibrosis) and the kidneys (interstitial nephritis with segmental glo-merulosclerosis). Long-term steroid therapy resulted in a significant slowing progression of the disease. This case was characterized by a prominent vasculitis which caused the misdiagnosis of ANCA-associated polyangiitis. Severe anemia and secondary immunodeficiency that were partially drug-induced due to the long-term steroid therapy were other manifestations of this disease. The advanced disease was complicated by lower respiratory tract infection, acute respiratory distress-syndrome, and multiple organ dysfunction that caused the patient's death. A comprehensive pathological investigation including immunohistochemistry had the crucial role for the final diagnosis.
KW - Acute respiratory distress-syndrome
KW - ANCA-associated polyangiitis
KW - Interstitial nephritis
KW - Pulmonary fibrosis
KW - Sarcoidosis
UR - http://www.scopus.com/inward/record.url?scp=85055664725&partnerID=8YFLogxK
U2 - 10.18093/0869-0189-2018-28-4-496-502
DO - 10.18093/0869-0189-2018-28-4-496-502
M3 - статья
AN - SCOPUS:85055664725
VL - 28
SP - 496
EP - 502
JO - ПУЛЬМОНОЛОГИЯ
JF - ПУЛЬМОНОЛОГИЯ
SN - 0869-0189
IS - 4
ER -
ID: 49976737