The analysis of the epidemic process associated with COVID-19 is carried out, possible scenarios of the development of events are presented. The most common anamnestic data, symptoms of infection, clinical picture and possible complications are described in detail. The features of the COVID-19 course in risk groups and the algorithms of administrative and medical actions that should underlie the provision of medical care to patients with cardiovascular, oncological, rheumatological diseases, pregnant women, etc. The section of diagnostics and examination features is of particular importance, since it includes not only the definition of the causative agent of the disease, but also the main indicators that determine the severity of the clinical picture, prognosis, the nature and extent of medical care. Considerable experience is presented in the clinical practice of computed tomography of the lungs, the method, the primary and early method for identifying not only lung lesions, but also the underlying disease - COVID-19. Information is presented from literary sources based on the experience of overcoming this formidable disease and its consequences by our colleagues, as well as the experience of domestic clinicians and scientists.