ПОВЫШЕНИЕ УРОВНЯ ТРНК У ДРОЖЖЕЙ, СОДЕРЖАЩИХ МУТАНТНЫЕ ФАКТОРЫ ТЕРМИНАЦИИ ТРАНСЛЯЦИИ ERFL И ERF3

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ПОВЫШЕНИЕ УРОВНЯ ТРНК У ДРОЖЖЕЙ, СОДЕРЖАЩИХ МУТАНТНЫЕ ФАКТОРЫ ТЕРМИНАЦИИ ТРАНСЛЯЦИИ ERFL И ERF3. / Журавлева, Г. А.; Москаленко, С. Е.; Шабельская, С. В.; Филипп, М.; Инге-Вечтомов, С. Г.

в: МОЛЕКУЛЯРНАЯ БИОЛОГИЯ, Том 40, № 4, 01.07.2006, стр. 724-730.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{7c46ace1dd88444685aa96830573449a,

title = "ПОВЫШЕНИЕ УРОВНЯ ТРНК У ДРОЖЖЕЙ, СОДЕРЖАЩИХ МУТАНТНЫЕ ФАКТОРЫ ТЕРМИНАЦИИ ТРАНСЛЯЦИИ ERFL И ERF3",

abstract = "Earlier we have characterized strains bearing mutations in essential genes SUP45 and SUP35 of yeast S. cerevisiae, encoding translation termination factors eRF1 and eRF3 respectively. In the present work nonsense-mutants on genes SUP45 and SUP35 have been compared by a level of eight tRNA: tRNATyr, tRNAGln, tRNATrp, tRNALeu and tRNAArg (previously described as potentially suppressor tRNA), and also tRNAPro, tRNAHis and tRNAGly. We have not revealed preferable increase in amount of natural suppressor tRNA. The majority of the investigated mutations leads to increase in a level of all investigated tRNA. The mechanisms providing viability of nonsense-mutants on essential genes SUP45 and SUP35 are discussed.",

author = "Журавлева, {Г. А.} and Москаленко, {С. Е.} and Шабельская, {С. В.} and М. Филипп and Инге-Вечтомов, {С. Г.}",

year = "2006",

month = jul,

day = "1",

language = "русский",

volume = "40",

pages = "724--730",

journal = "МОЛЕКУЛЯРНАЯ БИОЛОГИЯ",

issn = "0026-8984",

publisher = "Российская академия наук",

number = "4",

}

RIS

TY - JOUR

T1 - ПОВЫШЕНИЕ УРОВНЯ ТРНК У ДРОЖЖЕЙ, СОДЕРЖАЩИХ МУТАНТНЫЕ ФАКТОРЫ ТЕРМИНАЦИИ ТРАНСЛЯЦИИ ERFL И ERF3

AU - Журавлева, Г. А.

AU - Москаленко, С. Е.

AU - Шабельская, С. В.

AU - Филипп, М.

AU - Инге-Вечтомов, С. Г.

PY - 2006/7/1

Y1 - 2006/7/1

N2 - Earlier we have characterized strains bearing mutations in essential genes SUP45 and SUP35 of yeast S. cerevisiae, encoding translation termination factors eRF1 and eRF3 respectively. In the present work nonsense-mutants on genes SUP45 and SUP35 have been compared by a level of eight tRNA: tRNATyr, tRNAGln, tRNATrp, tRNALeu and tRNAArg (previously described as potentially suppressor tRNA), and also tRNAPro, tRNAHis and tRNAGly. We have not revealed preferable increase in amount of natural suppressor tRNA. The majority of the investigated mutations leads to increase in a level of all investigated tRNA. The mechanisms providing viability of nonsense-mutants on essential genes SUP45 and SUP35 are discussed.

AB - Earlier we have characterized strains bearing mutations in essential genes SUP45 and SUP35 of yeast S. cerevisiae, encoding translation termination factors eRF1 and eRF3 respectively. In the present work nonsense-mutants on genes SUP45 and SUP35 have been compared by a level of eight tRNA: tRNATyr, tRNAGln, tRNATrp, tRNALeu and tRNAArg (previously described as potentially suppressor tRNA), and also tRNAPro, tRNAHis and tRNAGly. We have not revealed preferable increase in amount of natural suppressor tRNA. The majority of the investigated mutations leads to increase in a level of all investigated tRNA. The mechanisms providing viability of nonsense-mutants on essential genes SUP45 and SUP35 are discussed.

UR - http://www.scopus.com/inward/record.url?scp=33749064449&partnerID=8YFLogxK

M3 - статья

C2 - 16913231

VL - 40

SP - 724

EP - 730

JO - МОЛЕКУЛЯРНАЯ БИОЛОГИЯ

JF - МОЛЕКУЛЯРНАЯ БИОЛОГИЯ

SN - 0026-8984

IS - 4

ER -

ID: 5024018