РОЛЬ КИШЕЧНОЙ МИКРОБИОТЫ В РАЗВИТИИ СЕРДЕЧНО-СОСУДИСТОЙ ПАТОЛОГИИ: ФОКУС НА МЕТАБОЛИТЫ И МАРКЕРЫ ПОВЫШЕННОЙ КИШЕЧНОЙ ПРОНИЦАЕМОСТИ И ВОСПАЛЕНИЯ КИШЕЧНОЙ СТЕНКИ

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РОЛЬ КИШЕЧНОЙ МИКРОБИОТЫ В РАЗВИТИИ СЕРДЕЧНО-СОСУДИСТОЙ ПАТОЛОГИИ: ФОКУС НА МЕТАБОЛИТЫ И МАРКЕРЫ ПОВЫШЕННОЙ КИШЕЧНОЙ ПРОНИЦАЕМОСТИ И ВОСПАЛЕНИЯ КИШЕЧНОЙ СТЕНКИ. / Kolesova, E. P.; Boyarinova, M. A.; Maslyanskiy, A. L.; Malyshkin, K. A.; Kibkalo, S. V.; Novikova, N. S.; Ermolenko, E. I.; Artomov, N. N.; Rotar, O. P.; Konradi, A. O.

в: АРТЕРИАЛЬНАЯ ГИПЕРТЕНЗИЯ, Том 29, № 5, 27.09.2023, стр. 442–455.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{3b4dd8da825b48129a8f2196b39f64b5,

title = "РОЛЬ КИШЕЧНОЙ МИКРОБИОТЫ В РАЗВИТИИ СЕРДЕЧНО-СОСУДИСТОЙ ПАТОЛОГИИ: ФОКУС НА МЕТАБОЛИТЫ И МАРКЕРЫ ПОВЫШЕННОЙ КИШЕЧНОЙ ПРОНИЦАЕМОСТИ И ВОСПАЛЕНИЯ КИШЕЧНОЙ СТЕНКИ",

abstract = "In recent years, an increasing number of studies have shown a close relationship between the composition and function of the microbiota and human health, including cardiovascular diseases (CVD). Increased intestinal permeability is one of the factors that can influence the state of the microbiota and also lead to the penetration of bacteria and their toxins into the bloodstream, causing systemic inflammation. Chronic inflammation, in turn, is accompanied by increased levels of cytokines, which can cause endothelial damage and lead to endothelial dysfunction. Metabolites of some bacteria can reduce the production of molecules that regulate vascular tone, such as nitric oxide, which can lead to vasoconstriction and hypertension. The review focuses on the connection between calprotectin, zonulin, and trimethylamine oxide with the risk of CVD, and also highlights possible methods for correcting the composition and function of the microbiota for the prevention of CVD.",

keywords = "arterial hypertension, calprotectin, cardiovascular diseases, chronic inflammation, endothelial dysfunction, gut microbiota, increased intestinal permeability, metabolites, trimethylamine oxide, zonulin",

author = "Kolesova, {E. P.} and Boyarinova, {M. A.} and Maslyanskiy, {A. L.} and Malyshkin, {K. A.} and Kibkalo, {S. V.} and Novikova, {N. S.} and Ermolenko, {E. I.} and Artomov, {N. N.} and Rotar, {O. P.} and Konradi, {A. O.}",

year = "2023",

month = sep,

day = "27",

doi = "10.18705/1607-419x-2023-29-5-442-455",

language = "русский",

volume = "29",

pages = "442–455",

journal = "Arterial Hypertension (Russian Federation)",

issn = "1607-419X",

publisher = "All-Russian Public Organization Antihypertensive League",

number = "5",

}

RIS

TY - JOUR

T1 - РОЛЬ КИШЕЧНОЙ МИКРОБИОТЫ В РАЗВИТИИ СЕРДЕЧНО-СОСУДИСТОЙ ПАТОЛОГИИ: ФОКУС НА МЕТАБОЛИТЫ И МАРКЕРЫ ПОВЫШЕННОЙ КИШЕЧНОЙ ПРОНИЦАЕМОСТИ И ВОСПАЛЕНИЯ КИШЕЧНОЙ СТЕНКИ

AU - Kolesova, E. P.

AU - Boyarinova, M. A.

AU - Maslyanskiy, A. L.

AU - Malyshkin, K. A.

AU - Kibkalo, S. V.

AU - Novikova, N. S.

AU - Ermolenko, E. I.

AU - Artomov, N. N.

AU - Rotar, O. P.

AU - Konradi, A. O.

PY - 2023/9/27

Y1 - 2023/9/27

N2 - In recent years, an increasing number of studies have shown a close relationship between the composition and function of the microbiota and human health, including cardiovascular diseases (CVD). Increased intestinal permeability is one of the factors that can influence the state of the microbiota and also lead to the penetration of bacteria and their toxins into the bloodstream, causing systemic inflammation. Chronic inflammation, in turn, is accompanied by increased levels of cytokines, which can cause endothelial damage and lead to endothelial dysfunction. Metabolites of some bacteria can reduce the production of molecules that regulate vascular tone, such as nitric oxide, which can lead to vasoconstriction and hypertension. The review focuses on the connection between calprotectin, zonulin, and trimethylamine oxide with the risk of CVD, and also highlights possible methods for correcting the composition and function of the microbiota for the prevention of CVD.

AB - In recent years, an increasing number of studies have shown a close relationship between the composition and function of the microbiota and human health, including cardiovascular diseases (CVD). Increased intestinal permeability is one of the factors that can influence the state of the microbiota and also lead to the penetration of bacteria and their toxins into the bloodstream, causing systemic inflammation. Chronic inflammation, in turn, is accompanied by increased levels of cytokines, which can cause endothelial damage and lead to endothelial dysfunction. Metabolites of some bacteria can reduce the production of molecules that regulate vascular tone, such as nitric oxide, which can lead to vasoconstriction and hypertension. The review focuses on the connection between calprotectin, zonulin, and trimethylamine oxide with the risk of CVD, and also highlights possible methods for correcting the composition and function of the microbiota for the prevention of CVD.

KW - arterial hypertension

KW - calprotectin

KW - cardiovascular diseases

KW - chronic inflammation

KW - endothelial dysfunction

KW - gut microbiota

KW - increased intestinal permeability

KW - metabolites

KW - trimethylamine oxide

KW - zonulin

UR - https://www.mendeley.com/catalogue/02bbec0d-416d-3114-9fea-eab77ba6bc46/

U2 - 10.18705/1607-419x-2023-29-5-442-455

DO - 10.18705/1607-419x-2023-29-5-442-455

M3 - статья

VL - 29

SP - 442

EP - 455

JO - Arterial Hypertension (Russian Federation)

JF - Arterial Hypertension (Russian Federation)

SN - 1607-419X

IS - 5

ER -

ID: 114640138