СОВРЕМЕННЫЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ КЛЕТОЧНОЙ ТЕРАПИИ НА ОСНОВЕ МЕЗЕНХИМНЫХ КЛЕТОК СЕРДЦА В ВОССТАНОВЛЕНИИ СОКРАТИТЕЛЬНОЙ ФУНКЦИИ МИОКАРДА

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СОВРЕМЕННЫЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ КЛЕТОЧНОЙ ТЕРАПИИ НА ОСНОВЕ МЕЗЕНХИМНЫХ КЛЕТОК СЕРДЦА В ВОССТАНОВЛЕНИИ СОКРАТИТЕЛЬНОЙ ФУНКЦИИ МИОКАРДА. / Docshin, P. M.; Bairqdar, A.; Malashicheva, A. B.

в: Complex Issues of Cardiovascular Diseases, Том 10, № 3, 25.09.2021, стр. 72-78.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{dd595d63463349efa6291d230b7e6245,

title = "СОВРЕМЕННЫЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ КЛЕТОЧНОЙ ТЕРАПИИ НА ОСНОВЕ МЕЗЕНХИМНЫХ КЛЕТОК СЕРДЦА В ВОССТАНОВЛЕНИИ СОКРАТИТЕЛЬНОЙ ФУНКЦИИ МИОКАРДА",

abstract = "Modern methods of treating heart failure are similar to the palliative care, since they mostly relieve the symptoms of the disease. The discovery of resident cardiac stem cells gave impetus to the development of “second generation” cell therapy, which quickly moved from animal research to clinical trials with critically ill patients. Many cardiac side population cells have been identified to have stem cells characteristics and some additional individual characteristics, both in vitro and in vivo. The results of clinical studies demonstrated that the stem cell treatment is safe, however, this type of cell-based therapy did not restore cardiac function. Its effects were limited to mildly improving left ventricular systolic pressure and reducing the scar area. Despite that, the promising nature of these therapeutic approaches for heart diseases have contributed to the development of next-generation cell therapy.",

keywords = "Cardiac mesenchymal stem cells, Cell therapy, Heart failure, Myocardial regeneration, Cardiac mesenchymal stem cells, Cell therapy, Heart failure, Myocardial regeneration",

author = "Docshin, {P. M.} and A. Bairqdar and Malashicheva, {A. B.}",

note = "Publisher Copyright: Copyright{\textcopyright} 2021, Japanese Society for Food Science and Technology",

year = "2021",

month = sep,

day = "25",

doi = "10.17802/2306-1278-2021-10-3-72-78",

language = "русский",

volume = "10",

pages = "72--78",

journal = "Комплексные проблемы сердечно-сосудистых заболеваний",

issn = "2306-1278",

publisher = "Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний",

number = "3",

}

RIS

TY - JOUR

T1 - СОВРЕМЕННЫЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ КЛЕТОЧНОЙ ТЕРАПИИ НА ОСНОВЕ МЕЗЕНХИМНЫХ КЛЕТОК СЕРДЦА В ВОССТАНОВЛЕНИИ СОКРАТИТЕЛЬНОЙ ФУНКЦИИ МИОКАРДА

AU - Docshin, P. M.

AU - Bairqdar, A.

AU - Malashicheva, A. B.

PY - 2021/9/25

Y1 - 2021/9/25

N2 - Modern methods of treating heart failure are similar to the palliative care, since they mostly relieve the symptoms of the disease. The discovery of resident cardiac stem cells gave impetus to the development of “second generation” cell therapy, which quickly moved from animal research to clinical trials with critically ill patients. Many cardiac side population cells have been identified to have stem cells characteristics and some additional individual characteristics, both in vitro and in vivo. The results of clinical studies demonstrated that the stem cell treatment is safe, however, this type of cell-based therapy did not restore cardiac function. Its effects were limited to mildly improving left ventricular systolic pressure and reducing the scar area. Despite that, the promising nature of these therapeutic approaches for heart diseases have contributed to the development of next-generation cell therapy.

AB - Modern methods of treating heart failure are similar to the palliative care, since they mostly relieve the symptoms of the disease. The discovery of resident cardiac stem cells gave impetus to the development of “second generation” cell therapy, which quickly moved from animal research to clinical trials with critically ill patients. Many cardiac side population cells have been identified to have stem cells characteristics and some additional individual characteristics, both in vitro and in vivo. The results of clinical studies demonstrated that the stem cell treatment is safe, however, this type of cell-based therapy did not restore cardiac function. Its effects were limited to mildly improving left ventricular systolic pressure and reducing the scar area. Despite that, the promising nature of these therapeutic approaches for heart diseases have contributed to the development of next-generation cell therapy.

KW - Cardiac mesenchymal stem cells

KW - Cell therapy

KW - Heart failure

KW - Myocardial regeneration

KW - Cardiac mesenchymal stem cells

KW - Cell therapy

KW - Heart failure

KW - Myocardial regeneration

UR - http://www.scopus.com/inward/record.url?scp=85116894612&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/d6a812dc-5004-386d-b483-bc59100761b7/

U2 - 10.17802/2306-1278-2021-10-3-72-78

DO - 10.17802/2306-1278-2021-10-3-72-78

M3 - статья

AN - SCOPUS:85116894612

VL - 10

SP - 72

EP - 78

JO - Комплексные проблемы сердечно-сосудистых заболеваний

JF - Комплексные проблемы сердечно-сосудистых заболеваний

SN - 2306-1278

IS - 3

ER -

ID: 87929110