The article deals with the course and results of the International scientific conference «Art and Culture of the Middle Ages: Heritage and Perspectives of Comprehension», as part of the international symposium «Actual Problems of Theory and History of Art», held by St. Petersburg State University together with Lomonosov Moscow State University and the leading museums of Russia in the mode of the Biennale. The event was organized with the support of the Russian Foundation for Basic Research (project No. 20-012-22040) and took place in St. Petersburg on October 26-31, 2020.