TY - JOUR

T1 - Уменьшение случайной составляющей погрешности количественных газохроматографических определений способом внешнего стандарта за счет использования сигнала растворителя

AU - Зенкевич, Игорь Георгиевич

AU - Бывшева, Софья Витальевна

AU - Герасимов, Артур Иванович

AU - Гладнев, Сергей Владиславович

AU - Григорьев, Михаил Вячеславович

AU - Губина, Нина Вячеславовна

AU - Диденко, Егор Александрович

AU - Казанцев, Александр Сергеевич

AU - Калуцкая, Татьяна Дмитриевна

AU - Катернюк, Елена Владиславовна

AU - Коблова, Алла Артуровна

AU - Крутин, Данил Вячеславович

AU - Малкова, Ксения Павловна

AU - Вахрушева, Светлана Алексеевна

AU - Одегова, Валерия Сергеевна

AU - Смирнова, Дарья Сергеевна

AU - Спиваковский, Валерий Алексеевич

AU - Терно, Павел Владимирович

N1 - Зенкевич И.Г. + 17 соавторов // Аналитика и контроль. 2022. Т. 26. № 2. С. 141-149.

PY - 2022/7/30

Y1 - 2022/7/30

N2 - Uncertainties of the results of quantitative determinations in gas chromatography using the methods based on the absolute peak areas (including the external standard method) are rather “sensitive” to the reproducibility of injections. The effective way to compensate for such errors is to introduce the additional standards into the samples, followed by replacing the absolute peak areas by their ratios to peak areas of the standards. It is important to underline that any constituents of the samples can be used as additional standards, including the solvents. Solvents can be used for these purposes even if the heights of their peaks are restric­ted when the analytical signals exceed the amplifier limits. Using the relative peak areas does not require any extra sample processing besides the registration of peak areas for solvents. Comparing the commonly known and modified methods of external stan­dard demonstrates that using the relative peak areas instead of the absolute ones does not influence the overall precision of determinations (according to the criterion “intro­duced-determined”) but improve the reproducibility by 2-3 times. The problem of increasing the reliability of such statistical evaluations of results is discussed and to solve it, it is proposed to change the “design” of the experiments. Instead of series of successive analyses of similar origin samples, the use of parallel determinations is preferable. This can be realized, for example, during the fulfillment of student’s practical works.

AB - Uncertainties of the results of quantitative determinations in gas chromatography using the methods based on the absolute peak areas (including the external standard method) are rather “sensitive” to the reproducibility of injections. The effective way to compensate for such errors is to introduce the additional standards into the samples, followed by replacing the absolute peak areas by their ratios to peak areas of the standards. It is important to underline that any constituents of the samples can be used as additional standards, including the solvents. Solvents can be used for these purposes even if the heights of their peaks are restric­ted when the analytical signals exceed the amplifier limits. Using the relative peak areas does not require any extra sample processing besides the registration of peak areas for solvents. Comparing the commonly known and modified methods of external stan­dard demonstrates that using the relative peak areas instead of the absolute ones does not influence the overall precision of determinations (according to the criterion “intro­duced-determined”) but improve the reproducibility by 2-3 times. The problem of increasing the reliability of such statistical evaluations of results is discussed and to solve it, it is proposed to change the “design” of the experiments. Instead of series of successive analyses of similar origin samples, the use of parallel determinations is preferable. This can be realized, for example, during the fulfillment of student’s practical works.

KW - количественный газохроматографический анализ

KW - способ внешнего стандарта

KW - растворитель как дополнительный стандарт

KW - уменьшение случайной составляющей погрешностей определений

KW - solvent as an additional standard

KW - decreasing the uncertainty of quantification

KW - quantitative chromatographic analysis

KW - external standard

UR - https://www.mendeley.com/catalogue/9e2306a8-421a-3468-bc20-9f72145a2c0d/

UR - http://www.scopus.com/inward/record.url?scp=85141388242&partnerID=8YFLogxK

U2 - 10.15826/analitika.2022.26.2.005

DO - 10.15826/analitika.2022.26.2.005

M3 - статья

VL - 26

SP - 141

EP - 149

JO - АНАЛИТИКА И КОНТРОЛЬ

JF - АНАЛИТИКА И КОНТРОЛЬ

SN - 2073-1442

IS - 2

ER -