Влияние физических нагрузок на иммунную систему в норме и при различных заболеваниях: обзор

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Влияние физических нагрузок на иммунную систему в норме и при различных заболеваниях: обзор. / Vologzhanin, D.A.; Golota, A.S.; Ignatenko, A.-M.I.; Kamilova, T.A.; Kovlen, D.V.; Usikova, E.V.; Shcherbak, S.G.

в: ВЕСТНИК ВОССТАНОВИТЕЛЬНОЙ МЕДИЦИНЫ, Том 24, № 1, 25.02.2025, стр. 91-102.

Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование

Author

Vologzhanin, D.A. ; Golota, A.S. ; Ignatenko, A.-M.I. ; Kamilova, T.A. ; Kovlen, D.V. ; Usikova, E.V. ; Shcherbak, S.G. / Влияние физических нагрузок на иммунную систему в норме и при различных заболеваниях: обзор. в: ВЕСТНИК ВОССТАНОВИТЕЛЬНОЙ МЕДИЦИНЫ. 2025 ; Том 24, № 1. стр. 91-102.

BibTeX

@article{636f54859de643feaf2b1a697c9e82b7,

title = "Влияние физических нагрузок на иммунную систему в норме и при различных заболеваниях: обзор",

abstract = "INTRODUCTION. Regular physical exercise has a beneficial effect on health, affecting all body systems and reducing morbidity. Muscle fiber activity during exercise helps reduce levels of inflammatory markers and stimulate anti-inflammatory responses. The ability to maintain homeostasis while exercising and adaptation to exercises depend on physical fitness, comorbidities and other factors, so the exercise program should be tailored to the individual. THE MAIN CONTENT OF THE REVIEW. Immune system activation in response to exercise is mediated by cytokine signaling. The main source of cytokines during physical activity is the skeletal muscles themselves. Cytokines produced by myocytes (myokines) during muscle contraction play a key role in providing communication between working muscles and other organs and tissues. Numerous studies have shown a positive effect of moderate intensity exercise on myokine secretion. People with chronic infectious or noninfectious diseases often demonstrate low-grade systemic inflammation and low levels of circulating myokines. Moderate intensity exercise has anti-inflammatory effects in inflammatory conditions and diseases. Exercise is a popular non-pharmacological adjunct to traditional treatments and rehabilitation for many diseases. CONCLUSION. Understanding the relationship between exercise modalities and myokine response helps to optimize treatment and rehabilitation recommendations for populations with different needs, such as patients with cancer, chronic inflammatory diseases, or post-viral infection syndromes. {\textcopyright} 2025 Elsevier B.V., All rights reserved.",

keywords = "chronic inflammatory diseases, cytokine, exercise, inflammation, myokine, rehabilitation, skeletal muscle, chronic inflammatory diseases, cytokine, exercise, inflammation, myokine, rehabilitation, skeletal muscle",

author = "D.A. Vologzhanin and A.S. Golota and A.-M.I. Ignatenko and T.A. Kamilova and D.V. Kovlen and E.V. Usikova and S.G. Shcherbak",

note = "Export Date: 01 November 2025; Cited By: 0; Correspondence Address: A.S. Golota; The Clinical Research Sector, Organizational and Methodological Department of Medical Rehabilitation, City Hospital No. 40 of the Kurortny District, Saint-Petersburg, Russian Federation; email: golotaa@yahoo.com",

year = "2025",

month = feb,

day = "25",

doi = "10.38025/2078-1962-2025-24-1-91-102",

language = "русский",

volume = "24",

pages = "91--102",

journal = "Vestnik Vosstanovitel'noj Mediciny",

issn = "2078-1962",

publisher = "НИЦКиР",

number = "1",

}

RIS

TY - JOUR

T1 - Влияние физических нагрузок на иммунную систему в норме и при различных заболеваниях: обзор

AU - Vologzhanin, D.A.

AU - Golota, A.S.

AU - Ignatenko, A.-M.I.

AU - Kamilova, T.A.

AU - Kovlen, D.V.

AU - Usikova, E.V.

AU - Shcherbak, S.G.

N1 - Export Date: 01 November 2025; Cited By: 0; Correspondence Address: A.S. Golota; The Clinical Research Sector, Organizational and Methodological Department of Medical Rehabilitation, City Hospital No. 40 of the Kurortny District, Saint-Petersburg, Russian Federation; email: golotaa@yahoo.com

PY - 2025/2/25

Y1 - 2025/2/25

N2 - INTRODUCTION. Regular physical exercise has a beneficial effect on health, affecting all body systems and reducing morbidity. Muscle fiber activity during exercise helps reduce levels of inflammatory markers and stimulate anti-inflammatory responses. The ability to maintain homeostasis while exercising and adaptation to exercises depend on physical fitness, comorbidities and other factors, so the exercise program should be tailored to the individual. THE MAIN CONTENT OF THE REVIEW. Immune system activation in response to exercise is mediated by cytokine signaling. The main source of cytokines during physical activity is the skeletal muscles themselves. Cytokines produced by myocytes (myokines) during muscle contraction play a key role in providing communication between working muscles and other organs and tissues. Numerous studies have shown a positive effect of moderate intensity exercise on myokine secretion. People with chronic infectious or noninfectious diseases often demonstrate low-grade systemic inflammation and low levels of circulating myokines. Moderate intensity exercise has anti-inflammatory effects in inflammatory conditions and diseases. Exercise is a popular non-pharmacological adjunct to traditional treatments and rehabilitation for many diseases. CONCLUSION. Understanding the relationship between exercise modalities and myokine response helps to optimize treatment and rehabilitation recommendations for populations with different needs, such as patients with cancer, chronic inflammatory diseases, or post-viral infection syndromes. © 2025 Elsevier B.V., All rights reserved.

AB - INTRODUCTION. Regular physical exercise has a beneficial effect on health, affecting all body systems and reducing morbidity. Muscle fiber activity during exercise helps reduce levels of inflammatory markers and stimulate anti-inflammatory responses. The ability to maintain homeostasis while exercising and adaptation to exercises depend on physical fitness, comorbidities and other factors, so the exercise program should be tailored to the individual. THE MAIN CONTENT OF THE REVIEW. Immune system activation in response to exercise is mediated by cytokine signaling. The main source of cytokines during physical activity is the skeletal muscles themselves. Cytokines produced by myocytes (myokines) during muscle contraction play a key role in providing communication between working muscles and other organs and tissues. Numerous studies have shown a positive effect of moderate intensity exercise on myokine secretion. People with chronic infectious or noninfectious diseases often demonstrate low-grade systemic inflammation and low levels of circulating myokines. Moderate intensity exercise has anti-inflammatory effects in inflammatory conditions and diseases. Exercise is a popular non-pharmacological adjunct to traditional treatments and rehabilitation for many diseases. CONCLUSION. Understanding the relationship between exercise modalities and myokine response helps to optimize treatment and rehabilitation recommendations for populations with different needs, such as patients with cancer, chronic inflammatory diseases, or post-viral infection syndromes. © 2025 Elsevier B.V., All rights reserved.

KW - chronic inflammatory diseases

KW - cytokine

KW - exercise

KW - inflammation

KW - myokine

KW - rehabilitation

KW - skeletal muscle

KW - chronic inflammatory diseases

KW - cytokine

KW - exercise

KW - inflammation

KW - myokine

KW - rehabilitation

KW - skeletal muscle

UR - https://www.mendeley.com/catalogue/337d0ced-75cf-3e6e-8d36-ba13dbd441fe/

U2 - 10.38025/2078-1962-2025-24-1-91-102

DO - 10.38025/2078-1962-2025-24-1-91-102

M3 - Обзорная статья

VL - 24

SP - 91

EP - 102

JO - Vestnik Vosstanovitel'noj Mediciny

JF - Vestnik Vosstanovitel'noj Mediciny

SN - 2078-1962

IS - 1

ER -

ID: 143612896