Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Прогностическая ценность шкал оценки хирургического риска у больных злокачественными опухолями легкого центральной локализации. / Земцова, Ирина Юрьевна; Атюков, Михаил Александрович; Пищик, Вадим Григорьевич; Яблонский, Павел Петрович; Яблонский, Петр Казимирович.
в: ХИРУРГИЯ. ЖУРНАЛ ИМ. Н.И. ПИРОГОВА, Том 9, № 9, 14.09.2026, стр. 116-124.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Прогностическая ценность шкал оценки хирургического риска у больных злокачественными опухолями легкого центральной локализации
AU - Земцова, Ирина Юрьевна
AU - Атюков, Михаил Александрович
AU - Пищик, Вадим Григорьевич
AU - Яблонский, Павел Петрович
AU - Яблонский, Петр Казимирович
PY - 2026/9/14
Y1 - 2026/9/14
N2 - Objective. To evaluate predictive value of current operative risk scales in non-small cell lung cancer (NSCLC) depending on tumor localization and identify independent predictors of 30-day mortality. Material and methods. A retrospective single-center cohort study enrolled 511 NSCLC patients who underwent anatomical lung resection (central tumors n=148, peripheral tumors n=363). Eurolung I/II, Modified Eurolung II, Thoracoscore, SABCIP, and ESOS scales were assessed by ROC analysis using a single Youden-derived cut-off applied uniformly across subgroups. Complications were classified as minor (Clavien-Dindo I–IIIa) or major (IIIb–V). Risk factors were identified by logistic regression. Results. Thirty-day mortality was 2.3% (12/511). In centrally located tumors, AUC fell to 0.581–0.729 versus 0.690–0.918 in peripheral tumors. Specificity dropped to 38–62%. Central localization showed a stepwise increase in prognostic impact: non-significant for minor complications (OR=1.249; p=0.289), significant for major complications (OR=2.604; 95% CI 1.209–5.609; p=0.014), and the strongest for mortality (OR=5.129; 95% CI 1.520–17.302; p=0.008). Multivariable analysis identified central localization (OR=3.593; p=0.046) and FEV1
AB - Objective. To evaluate predictive value of current operative risk scales in non-small cell lung cancer (NSCLC) depending on tumor localization and identify independent predictors of 30-day mortality. Material and methods. A retrospective single-center cohort study enrolled 511 NSCLC patients who underwent anatomical lung resection (central tumors n=148, peripheral tumors n=363). Eurolung I/II, Modified Eurolung II, Thoracoscore, SABCIP, and ESOS scales were assessed by ROC analysis using a single Youden-derived cut-off applied uniformly across subgroups. Complications were classified as minor (Clavien-Dindo I–IIIa) or major (IIIb–V). Risk factors were identified by logistic regression. Results. Thirty-day mortality was 2.3% (12/511). In centrally located tumors, AUC fell to 0.581–0.729 versus 0.690–0.918 in peripheral tumors. Specificity dropped to 38–62%. Central localization showed a stepwise increase in prognostic impact: non-significant for minor complications (OR=1.249; p=0.289), significant for major complications (OR=2.604; 95% CI 1.209–5.609; p=0.014), and the strongest for mortality (OR=5.129; 95% CI 1.520–17.302; p=0.008). Multivariable analysis identified central localization (OR=3.593; p=0.046) and FEV1
UR - https://www.mendeley.com/catalogue/3a777fdc-1854-31ca-9666-234b56523c18/
U2 - 10.17116/hirurgia2026092116
DO - 10.17116/hirurgia2026092116
M3 - статья
VL - 9
SP - 116
EP - 124
JO - ХИРУРГИЯ. ЖУРНАЛ ИМ. Н.И. ПИРОГОВА
JF - ХИРУРГИЯ. ЖУРНАЛ ИМ. Н.И. ПИРОГОВА
SN - 0023-1207
IS - 9
ER -
ID: 161151812