The mineral assemblage including native gold, chalcopyrite, sphalerite, pyrite, as well as minerals of the garnet group is identified as a result of studies of the Anmandykan 2nd stream basin in the northeastern part of the Okhotsk region of the Khabarovsk krai. It is established that Pb mineralization has no gold potential. There is, at least, one primary source, which is possibly associated with quartz (rarely quartz-carbonate) veins. The results of mineralogical and geochemical analyzes of heavy concentrates in the studied area are comparable with each other, which will reduce labor costs during geological exploration to search for primary gold mineralization.