Влияние прогностических факторов на показатели выживаемости у больных с несветлоклеточным почечно-клеточным раком.

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Влияние прогностических факторов на показатели выживаемости у больных с несветлоклеточным почечно-клеточным раком. / Семенов, Дмитрий Владимирович ; Орлова, Рашида Вахидовна; Широкорад, Валерий Иванович; Кострицкий, Станислав Викторович.

в: СИБИРСКИЙ ОНКОЛОГИЧЕСКИЙ ЖУРНАЛ, Том 24, № 1, 1, 18.03.2025, стр. 49-58.

Результаты исследований: Научные публикации в периодических изданиях › статья

BibTeX

@article{044b1b0dacd94affaf36cdf33c46ad9e,

title = "Влияние прогностических факторов на показатели выживаемости у больных с несветлоклеточным почечно-клеточным раком.",

abstract = "Currently, there is a need to search for new prognostic factors in patients with non-clear cell renal cell carcinoma (nccRCC) for personalized therapy to improve survival rates. Objective: to study the most important prognostic factors influencing survival rates in patients with nccRCC. Material and Methods. A retrospective analysis of the data of 114 patients with nccRCC treated at the Moscow City Oncologic Hospital No. 62 in Moscow and the City Clinical Oncology Center (St. Petersburg) from 2006 to 2022 was carried out. Papillary cancer was detected in 46 (40.3 %) patients, chromophobe cancer in 19 (16.7 %) and sarcomotoid cancer in 49 (43 %) patients. Seventy-four (64.9 %) patients had an unfavourable prognosis according to International RCC Data Base Consortium, with low-differentiated tumors in 72 (63.2 %) patients. Multiple metastases were detected in 88 (77.2 %) patients. The study investigated clinical and morphologic prognostic factors influencing survival rates in nccRCC patients. Results. The 3-and 5-year overall survival (OS) rates in nccRCC patients were 27 % [95 % CI 20–37 %] and 10 % [95 % CI 5–18 %], respectively. Univariate analysis in patients with nccRCC revealed that survival was negatively affected by tumor histological subtype (p",

keywords = "non-clear cell cancer, overall survival, prognostic factors",

author = "Семенов, {Дмитрий Владимирович} and Орлова, {Рашида Вахидовна} and Широкорад, {Валерий Иванович} and Кострицкий, {Станислав Викторович}",

year = "2025",

month = mar,

day = "18",

doi = "10.21294/1814-4861-2025-24-1-49-58",

language = "русский",

volume = "24",

pages = "49--58",

journal = "СИБИРСКИЙ ОНКОЛОГИЧЕСКИЙ ЖУРНАЛ",

issn = "1814-4861",

publisher = "Томский национальный исследовательский медицинский центр Российской академии наук",

number = "1",

}

RIS

TY - JOUR

T1 - Влияние прогностических факторов на показатели выживаемости у больных с несветлоклеточным почечно-клеточным раком.

AU - Семенов, Дмитрий Владимирович

AU - Орлова, Рашида Вахидовна

AU - Широкорад, Валерий Иванович

AU - Кострицкий, Станислав Викторович

PY - 2025/3/18

Y1 - 2025/3/18

N2 - Currently, there is a need to search for new prognostic factors in patients with non-clear cell renal cell carcinoma (nccRCC) for personalized therapy to improve survival rates. Objective: to study the most important prognostic factors influencing survival rates in patients with nccRCC. Material and Methods. A retrospective analysis of the data of 114 patients with nccRCC treated at the Moscow City Oncologic Hospital No. 62 in Moscow and the City Clinical Oncology Center (St. Petersburg) from 2006 to 2022 was carried out. Papillary cancer was detected in 46 (40.3 %) patients, chromophobe cancer in 19 (16.7 %) and sarcomotoid cancer in 49 (43 %) patients. Seventy-four (64.9 %) patients had an unfavourable prognosis according to International RCC Data Base Consortium, with low-differentiated tumors in 72 (63.2 %) patients. Multiple metastases were detected in 88 (77.2 %) patients. The study investigated clinical and morphologic prognostic factors influencing survival rates in nccRCC patients. Results. The 3-and 5-year overall survival (OS) rates in nccRCC patients were 27 % [95 % CI 20–37 %] and 10 % [95 % CI 5–18 %], respectively. Univariate analysis in patients with nccRCC revealed that survival was negatively affected by tumor histological subtype (p

AB - Currently, there is a need to search for new prognostic factors in patients with non-clear cell renal cell carcinoma (nccRCC) for personalized therapy to improve survival rates. Objective: to study the most important prognostic factors influencing survival rates in patients with nccRCC. Material and Methods. A retrospective analysis of the data of 114 patients with nccRCC treated at the Moscow City Oncologic Hospital No. 62 in Moscow and the City Clinical Oncology Center (St. Petersburg) from 2006 to 2022 was carried out. Papillary cancer was detected in 46 (40.3 %) patients, chromophobe cancer in 19 (16.7 %) and sarcomotoid cancer in 49 (43 %) patients. Seventy-four (64.9 %) patients had an unfavourable prognosis according to International RCC Data Base Consortium, with low-differentiated tumors in 72 (63.2 %) patients. Multiple metastases were detected in 88 (77.2 %) patients. The study investigated clinical and morphologic prognostic factors influencing survival rates in nccRCC patients. Results. The 3-and 5-year overall survival (OS) rates in nccRCC patients were 27 % [95 % CI 20–37 %] and 10 % [95 % CI 5–18 %], respectively. Univariate analysis in patients with nccRCC revealed that survival was negatively affected by tumor histological subtype (p

KW - non-clear cell cancer

KW - overall survival

KW - prognostic factors

UR - https://www.mendeley.com/catalogue/9897ab88-da22-3d61-9bbd-15082ade4c92/

U2 - 10.21294/1814-4861-2025-24-1-49-58

DO - 10.21294/1814-4861-2025-24-1-49-58

M3 - статья

VL - 24

SP - 49

EP - 58

JO - СИБИРСКИЙ ОНКОЛОГИЧЕСКИЙ ЖУРНАЛ

JF - СИБИРСКИЙ ОНКОЛОГИЧЕСКИЙ ЖУРНАЛ

SN - 1814-4861

IS - 1

M1 - 1

ER -

ID: 134409170