The efficiency of the methods of necrectomy for deep frostbite was analyzed according to the data of outcomes of surgical treatment of 272 patients with cold injury. It was shown that dissection of necrotic tissue in deep frostbite using modern physical techniques (electrosurgical, radiosurgical and argon-plasma dissector) improved immediate results of surgical treatment (due to decreased intraoperative blood loss, frequency of suppuration, cases of amputation, time of hospitalization) and optimized the wound process (by reducing the microbial contamination of the wounds) and accelerated the proliferative phase of regeneration.