Морфологическая диагностика инфекционных осложнений после трансплантации аллогенных гемопоэтических стволовых клеток

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Морфологическая диагностика инфекционных осложнений после трансплантации аллогенных гемопоэтических стволовых клеток. / Baram, D.V.; Krysyuk, O.B.

в: HIV Infection and Immunosuppressive Disorders, Том 17, № 2, 2025, стр. 102-106.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{93e4e29c71bf4004a04f5646dbaa6d6c,

title = "Морфологическая диагностика инфекционных осложнений после трансплантации аллогенных гемопоэтических стволовых клеток",

abstract = "This clinical case presents a combined herpes virus infection (cytomegalovirus and HSV-2) in a 55-year-old female patient after allogeneic hematopoietic stem cell transplantation, which manifested as colitis. Despite prophylactic use of acyclovir, viral reactivation occurred, indicating the need for long-term antiviral prophylaxis. The diagnostic process was complicated by non-speciﬁc clinical presentation and negative results of polymerase chain reaction and serological tests, which required morphological and immunohistochemical examination of biopsy specimens. This clinical case demonstrates the peculiarities of diagnosis and treatment of herpes virus infections in immunocompromised patients after bone marrow transplantation. {\textcopyright} Барам Д.В., Крысюк О.Б., 2025 г.",

keywords = "bone marrow transplant, herpes virus infections, pathomorphological examination",

author = "D.V. Baram and O.B. Krysyuk",

note = "Export Date: 16 February 2026; Cited By: 0; Correspondence Address: D.V. Baram; Russian Research Institute of Hematology and Transfusiology, St. Petersburg, Russian Federation; email: bdv150595@yandex.ru",

year = "2025",

doi = "10.22328/2077-9828-2025-17-2-102-106",

language = "русский",

volume = "17",

pages = "102--106",

journal = "ВИЧ-инфекция и иммуносупрессии",

issn = "2077-9828",

publisher = "БАЛТИЙСКИЙ МЕДИЦИНСКИЙ ОБРАЗОВАТЕЛЬНЫЙ ЦЕНТР",

number = "2",

}

RIS

TY - JOUR

T1 - Морфологическая диагностика инфекционных осложнений после трансплантации аллогенных гемопоэтических стволовых клеток

AU - Baram, D.V.

AU - Krysyuk, O.B.

N1 - Export Date: 16 February 2026; Cited By: 0; Correspondence Address: D.V. Baram; Russian Research Institute of Hematology and Transfusiology, St. Petersburg, Russian Federation; email: bdv150595@yandex.ru

PY - 2025

Y1 - 2025

N2 - This clinical case presents a combined herpes virus infection (cytomegalovirus and HSV-2) in a 55-year-old female patient after allogeneic hematopoietic stem cell transplantation, which manifested as colitis. Despite prophylactic use of acyclovir, viral reactivation occurred, indicating the need for long-term antiviral prophylaxis. The diagnostic process was complicated by non-speciﬁc clinical presentation and negative results of polymerase chain reaction and serological tests, which required morphological and immunohistochemical examination of biopsy specimens. This clinical case demonstrates the peculiarities of diagnosis and treatment of herpes virus infections in immunocompromised patients after bone marrow transplantation. © Барам Д.В., Крысюк О.Б., 2025 г.

AB - This clinical case presents a combined herpes virus infection (cytomegalovirus and HSV-2) in a 55-year-old female patient after allogeneic hematopoietic stem cell transplantation, which manifested as colitis. Despite prophylactic use of acyclovir, viral reactivation occurred, indicating the need for long-term antiviral prophylaxis. The diagnostic process was complicated by non-speciﬁc clinical presentation and negative results of polymerase chain reaction and serological tests, which required morphological and immunohistochemical examination of biopsy specimens. This clinical case demonstrates the peculiarities of diagnosis and treatment of herpes virus infections in immunocompromised patients after bone marrow transplantation. © Барам Д.В., Крысюк О.Б., 2025 г.

KW - bone marrow transplant

KW - herpes virus infections

KW - pathomorphological examination

U2 - 10.22328/2077-9828-2025-17-2-102-106

DO - 10.22328/2077-9828-2025-17-2-102-106

M3 - статья

VL - 17

SP - 102

EP - 106

JO - ВИЧ-инфекция и иммуносупрессии

JF - ВИЧ-инфекция и иммуносупрессии

SN - 2077-9828

IS - 2

ER -

ID: 148839062