Urolithiasis and its symptomatic recurrences are one of the most common urological diseases in people of working age and is characterised by a high prevalence of complicated forms, in some cases leading to disability of the patient. Despite the fairly high study of the problem, the treatment of urolithiasis is still quite a serious task for clinicians. Optimal is a combination of medication and non-medication methods of treatment. The questions of introduction of new methods of pain syndrome correction and improvement of stone excretion in uncomplicated form of urolithiasis in order to reduce the medication load on the organism, prevent further increase in the size of concrements, and, as a consequence, the development of complications requiring surgical intervention, as well as the search for ways to prevent complications is of interest to the medical community. A case from practice is described, dedicated to the isolated use (monotherapy) of osteopathic correction in a patient with urolithiasis.