АВТОМАТИЧЕСКИЙ АНАЛИЗ ДАННЫХ ПОВЕДЕНЧЕСКОГО ТЕСТА “ВОДНЫЙ ЛАБИРИНТ МОРРИСА”

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АВТОМАТИЧЕСКИЙ АНАЛИЗ ДАННЫХ ПОВЕДЕНЧЕСКОГО ТЕСТА “ВОДНЫЙ ЛАБИРИНТ МОРРИСА”. / Chernyuk, D. P.; Zorin, A. G.; Derevtsova, K. Z.; Efimova, E. V.; Prikhodko, V. A.; Sysoev, Y. I.; Vlasova, O. L.; Bolsunovskaia, M. V.; Bezprozvanny, I. B.

в: Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova, Том 71, № 1, 2021, стр. 126-135.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Author

Chernyuk, D. P. ; Zorin, A. G. ; Derevtsova, K. Z. ; Efimova, E. V. ; Prikhodko, V. A. ; Sysoev, Y. I. ; Vlasova, O. L. ; Bolsunovskaia, M. V. ; Bezprozvanny, I. B. / АВТОМАТИЧЕСКИЙ АНАЛИЗ ДАННЫХ ПОВЕДЕНЧЕСКОГО ТЕСТА “ВОДНЫЙ ЛАБИРИНТ МОРРИСА”. в: Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 2021 ; Том 71, № 1. стр. 126-135.

BibTeX

@article{e3019b96a21c44688e9e643cdf8f553f,

title = "АВТОМАТИЧЕСКИЙ АНАЛИЗ ДАННЫХ ПОВЕДЕНЧЕСКОГО ТЕСТА “ВОДНЫЙ ЛАБИРИНТ МОРРИСА”",

abstract = "The Morris water maze behavioral test is a universal method for testing cognitive functions in experimental rodents, and it is especially effective in detecting deviations in memory functions and learning, which makes it indispensable in the study of neurodegenerative diseases and testing potential therapeutic agents aimed at improving cognitive function. However, despite the wide range of possible applications, data analysis makes the use of this test quite labor intensive. Currently, automated tracking and analysis programs are used to analyze rodent movements. But all known quality programs are the property of foreign commercial companies and expensive. Thus, our goal was to develop and create an available quality product, which will allow Russian scientist to carry out research using various options of the {"}Morris water maze{"}. In this article, we describe in detail creation of new software that we called Minopontikos. We also compared performance of Minopontikos with two widely used commercial packages: VideoMot and EthoVision. We established that Minopontikos was able to quickly and accurately detect the trajectory of animal moving in the water and to provide parameters for evaluating the cognitive functions of memory and learning. Overall performance of Minopontikos was comparable to commercial packages.",

keywords = "Automated analysis, Behavior, Behavioral test, Morris water maze, Mouse, Tracking, mouse, behavioral test, behavior, automated analysis, tracking",

author = "Chernyuk, {D. P.} and Zorin, {A. G.} and Derevtsova, {K. Z.} and Efimova, {E. V.} and Prikhodko, {V. A.} and Sysoev, {Y. I.} and Vlasova, {O. L.} and Bolsunovskaia, {M. V.} and Bezprozvanny, {I. B.}",

year = "2021",

doi = "10.31857/s0044467721010044",

language = "русский",

volume = "71",

pages = "126--135",

journal = "ЖУРНАЛ ВЫСШЕЙ НЕРВНОЙ ДЕЯТЕЛЬНОСТИ ИМ. И.П. ПАВЛОВА",

issn = "0044-4677",

publisher = "Издательство {"}Наука{"}",

number = "1",

}

RIS

TY - JOUR

T1 - АВТОМАТИЧЕСКИЙ АНАЛИЗ ДАННЫХ ПОВЕДЕНЧЕСКОГО ТЕСТА “ВОДНЫЙ ЛАБИРИНТ МОРРИСА”

AU - Chernyuk, D. P.

AU - Zorin, A. G.

AU - Derevtsova, K. Z.

AU - Efimova, E. V.

AU - Prikhodko, V. A.

AU - Sysoev, Y. I.

AU - Vlasova, O. L.

AU - Bolsunovskaia, M. V.

AU - Bezprozvanny, I. B.

PY - 2021

Y1 - 2021

N2 - The Morris water maze behavioral test is a universal method for testing cognitive functions in experimental rodents, and it is especially effective in detecting deviations in memory functions and learning, which makes it indispensable in the study of neurodegenerative diseases and testing potential therapeutic agents aimed at improving cognitive function. However, despite the wide range of possible applications, data analysis makes the use of this test quite labor intensive. Currently, automated tracking and analysis programs are used to analyze rodent movements. But all known quality programs are the property of foreign commercial companies and expensive. Thus, our goal was to develop and create an available quality product, which will allow Russian scientist to carry out research using various options of the "Morris water maze". In this article, we describe in detail creation of new software that we called Minopontikos. We also compared performance of Minopontikos with two widely used commercial packages: VideoMot and EthoVision. We established that Minopontikos was able to quickly and accurately detect the trajectory of animal moving in the water and to provide parameters for evaluating the cognitive functions of memory and learning. Overall performance of Minopontikos was comparable to commercial packages.

AB - The Morris water maze behavioral test is a universal method for testing cognitive functions in experimental rodents, and it is especially effective in detecting deviations in memory functions and learning, which makes it indispensable in the study of neurodegenerative diseases and testing potential therapeutic agents aimed at improving cognitive function. However, despite the wide range of possible applications, data analysis makes the use of this test quite labor intensive. Currently, automated tracking and analysis programs are used to analyze rodent movements. But all known quality programs are the property of foreign commercial companies and expensive. Thus, our goal was to develop and create an available quality product, which will allow Russian scientist to carry out research using various options of the "Morris water maze". In this article, we describe in detail creation of new software that we called Minopontikos. We also compared performance of Minopontikos with two widely used commercial packages: VideoMot and EthoVision. We established that Minopontikos was able to quickly and accurately detect the trajectory of animal moving in the water and to provide parameters for evaluating the cognitive functions of memory and learning. Overall performance of Minopontikos was comparable to commercial packages.

KW - Automated analysis

KW - Behavior

KW - Behavioral test

KW - Morris water maze

KW - Mouse

KW - Tracking

KW - mouse

KW - behavioral test

KW - behavior

KW - automated analysis

KW - tracking

UR - http://www.scopus.com/inward/record.url?scp=85105468354&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/cc34e691-d20f-3480-9ed9-183676c25981/

U2 - 10.31857/s0044467721010044

DO - 10.31857/s0044467721010044

M3 - статья

AN - SCOPUS:85105468354

VL - 71

SP - 126

EP - 135

JO - ЖУРНАЛ ВЫСШЕЙ НЕРВНОЙ ДЕЯТЕЛЬНОСТИ ИМ. И.П. ПАВЛОВА

JF - ЖУРНАЛ ВЫСШЕЙ НЕРВНОЙ ДЕЯТЕЛЬНОСТИ ИМ. И.П. ПАВЛОВА

SN - 0044-4677

IS - 1

ER -

ID: 85902003