Результаты исследований: Научные публикации в периодических изданиях › Обзор литературы › Рецензирование
Модели трансплантации легких для доклинических исследований (обзор литературы). / Bunenkov, N.S.; Akopov, A.L.; Popov, S.V.; Karpov, A.A.; Minasyan, S.M.; Gusejnov, R.G.; Perepelitsa, V.V.; Galagudza, M.M.
в: ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ, Том 26, № 3, 20.05.2024, стр. 183-194.Результаты исследований: Научные публикации в периодических изданиях › Обзор литературы › Рецензирование
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TY - JOUR
T1 - Модели трансплантации легких для доклинических исследований (обзор литературы)
AU - Bunenkov, N.S.
AU - Akopov, A.L.
AU - Popov, S.V.
AU - Karpov, A.A.
AU - Minasyan, S.M.
AU - Gusejnov, R.G.
AU - Perepelitsa, V.V.
AU - Galagudza, M.M.
N1 - Export Date: 21 October 2024 Адрес для корреспонденции: Bunenkov, N.S.6–8, L’va Tolstogo str., Russian Federation; эл. почта: bunenkov2006@gmail.com
PY - 2024/5/20
Y1 - 2024/5/20
N2 - Lung transplantation (LT) is the only treatment for many end-stage lung diseases. Despite significant progress in transplantology and surgery, LT remains a high-tech surgical procedure performed at select research centers. Primary graft dysfunction, acute rejection, and chronic lung allograft dysfunction are serious problems that can worsen lung transplant outcomes significantly. Using animal models in experimental studies to investigate these pathologic conditions is one of the more rational approaches. A literature review was conducted in order to select a suitable model that reproduces pathologic processes developing after LT. The literature was searched and analyzed in MEDLINE and Elibrary databases, and the US National Institute of Health guidelines for the period up to December 2023 were reviewed. It was found that the most frequently used models are small laboratory animal models (without LT) and large animal models (with LT). © 2024 Russian Transplant Society. All rights reserved.
AB - Lung transplantation (LT) is the only treatment for many end-stage lung diseases. Despite significant progress in transplantology and surgery, LT remains a high-tech surgical procedure performed at select research centers. Primary graft dysfunction, acute rejection, and chronic lung allograft dysfunction are serious problems that can worsen lung transplant outcomes significantly. Using animal models in experimental studies to investigate these pathologic conditions is one of the more rational approaches. A literature review was conducted in order to select a suitable model that reproduces pathologic processes developing after LT. The literature was searched and analyzed in MEDLINE and Elibrary databases, and the US National Institute of Health guidelines for the period up to December 2023 were reviewed. It was found that the most frequently used models are small laboratory animal models (without LT) and large animal models (with LT). © 2024 Russian Transplant Society. All rights reserved.
KW - acute lung rejection
KW - chronic lung rejection
KW - lung transplantation model
KW - primary graft dysfunction
KW - chronic lung allograft dysfunction
KW - experimental animal
KW - human
KW - lung graft rejection
KW - lung transplantation
KW - medical research
KW - outcome assessment
KW - practice guideline
KW - Review
KW - acute lung rejection
KW - chronic lung rejection
KW - lung transplantation model
KW - primary graft dysfunction
UR - https://www.mendeley.com/catalogue/b58661ed-6b5b-3928-8940-74787a849429/
U2 - 10.15825/1995-1191-2024-3-183-194
DO - 10.15825/1995-1191-2024-3-183-194
M3 - Обзор литературы
VL - 26
SP - 183
EP - 194
JO - ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ
JF - ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ
SN - 1995-1191
IS - 3
ER -
ID: 126226325