TY - JOUR

T1 - Двойной диагноз: «депрессия» и «расстройство употребления алкоголя».

AU - Сиволап, Юрий Павлович

AU - Крупицкий, Евгений Михайлович

AU - Менделевич, Владимир Давыдович

AU - Рыбакова, Ксения Валерьевна

AU - Егоров, Алексей Юрьевич

AU - Усов, Григорий Михайловия

PY - 2021

Y1 - 2021

N2 - A combination of depression and alcohol use disorder (AUD) is a typical and most common example of a dual diagnosis at the intersection of general psychiatry and addiction psychiatry. A comorbidity of depression and AUD is more common than it can be brought about by mere coincidence, which might be explained to some extent by the synergetic effect of both diseases, with each of them complicating the course and worsening the prognosis of the other. Treatment protocols for patients with depression and comorbid AUD include antidepressants, specific medications for alcohol dependence, and psychotherapy. The first-line antidepressants in the treatment of patients with a comorbid combination of depression and alcohol use disorder, as in other clinical situations implying use of antidepressants, are selective serotonin reuptake inhibitors (SSRIs). Fluvoxamine has certain advantages over the other SSRIs in the treatment of patients with a depression and comorbid AUD.

AB - A combination of depression and alcohol use disorder (AUD) is a typical and most common example of a dual diagnosis at the intersection of general psychiatry and addiction psychiatry. A comorbidity of depression and AUD is more common than it can be brought about by mere coincidence, which might be explained to some extent by the synergetic effect of both diseases, with each of them complicating the course and worsening the prognosis of the other. Treatment protocols for patients with depression and comorbid AUD include antidepressants, specific medications for alcohol dependence, and psychotherapy. The first-line antidepressants in the treatment of patients with a comorbid combination of depression and alcohol use disorder, as in other clinical situations implying use of antidepressants, are selective serotonin reuptake inhibitors (SSRIs). Fluvoxamine has certain advantages over the other SSRIs in the treatment of patients with a depression and comorbid AUD.

KW - alcohol use disorder

KW - antidepressants

KW - compliance

KW - depression

KW - fluvoxamine

KW - selective serotonin reuptake inhibitors

KW - alcohol use disorder

KW - antidepressants

KW - compliance

KW - depression

KW - fluvoxamine

KW - selective serotonin reuptake inhibitors

UR - http://www.scopus.com/inward/record.url?scp=85115279506&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/93bca50b-76eb-3cd9-95a3-a114f7e81e71/

U2 - 10.17116/jnevro2021121071135

DO - 10.17116/jnevro2021121071135

M3 - статья

VL - 121

SP - 135

EP - 140

JO - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА

JF - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА

SN - 1997-7298

IS - 7

ER -