The quality of life (QL) study has been conducted using the WHOQOL-100 questionnaire in 146 patients with epilepsy in the process of their rehabilitation. Before treatment and restorative interventions, the majority of the patients evaluated their QL as moderate and low depending on the type, frequency and severity of seizures as well as on the age of the disease onset. During restorative therapy, the QL scores increased in physical, psychological and social relationship domains and some indices correlated with the results of restorative treatment.