Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Маркеры активности болезни Стилла взрослых. / Myachikova, Valentina Yu; Tkachenko, Olga Yu; Lapin, Sergey V.; Kuvardin, E. S.; Maslyanskiy, Aleksey L.
в: НАУЧНО-ПРАКТИЧЕСКАЯ РЕВМАТОЛОГИЯ, Том 60, № 3, 09.07.2022, стр. 341-346.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Маркеры активности болезни Стилла взрослых
AU - Myachikova, Valentina Yu
AU - Tkachenko, Olga Yu
AU - Lapin, Sergey V.
AU - Kuvardin, E. S.
AU - Maslyanskiy, Aleksey L.
N1 - Publisher Copyright: © 2022 Ima-Press Publishing House. All rights reserved.
PY - 2022/7/9
Y1 - 2022/7/9
N2 - Adult-onset Still’s disease (AOSD) is a rare complex autoinflammatory disease of unknown etiology. The main problem, practitioners have been facing with when researching AOSD, is the lack of developed approaches to assessing the activity of the disease. Traditionally used standard markers of inflammation do not always reflect the real activity of AOSD, especially when a patient is already receiving anti-inflammatory therapy. The article presents original data on the study of biomarkers: interleukin-1 beta (IL-1b), interleukin-6 (IL-6), interleukin-18 (IL-18), ferritin, glycosylated ferritin, calprotectin, procalcitonin compared with C-reactive protein, leukocyte and neutrophil counts in patients with moderate and high activity of AOSD. The relationship between inflammatory biomarkers and the Pouchot systemic score was evaluated to identify promising laboratory indicators of disease activity.
AB - Adult-onset Still’s disease (AOSD) is a rare complex autoinflammatory disease of unknown etiology. The main problem, practitioners have been facing with when researching AOSD, is the lack of developed approaches to assessing the activity of the disease. Traditionally used standard markers of inflammation do not always reflect the real activity of AOSD, especially when a patient is already receiving anti-inflammatory therapy. The article presents original data on the study of biomarkers: interleukin-1 beta (IL-1b), interleukin-6 (IL-6), interleukin-18 (IL-18), ferritin, glycosylated ferritin, calprotectin, procalcitonin compared with C-reactive protein, leukocyte and neutrophil counts in patients with moderate and high activity of AOSD. The relationship between inflammatory biomarkers and the Pouchot systemic score was evaluated to identify promising laboratory indicators of disease activity.
KW - adult-onset Still’s disease
KW - AOSD
KW - calgranulin
KW - glycosylated ferritin
KW - interleukin-18
KW - interleukin-1β
KW - interleukin-6
KW - procalcitonin
KW - AOSD
KW - adult-onset Still’s disease
KW - calgranulin
KW - glycosylated ferritin
KW - interleukin-18
KW - interleukin-1β
KW - interleukin-6
KW - procalcitonin
UR - http://www.scopus.com/inward/record.url?scp=85135232698&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/3c0aaae5-e276-3bd1-9a62-7ef81ad7f5ca/
U2 - 10.47360/1995-4484-2022-341-346
DO - 10.47360/1995-4484-2022-341-346
M3 - статья
VL - 60
SP - 341
EP - 346
JO - НАУЧНО-ПРАКТИЧЕСКАЯ РЕВМАТОЛОГИЯ
JF - НАУЧНО-ПРАКТИЧЕСКАЯ РЕВМАТОЛОГИЯ
SN - 1995-4484
IS - 3
ER -
ID: 100704057