Currently, gluten enteropathy (celiac disease) is one of the most urgent diseases with a genetically determined, autoimmune profile, which significantly reduces the social adaptation and quality of life of patients. In recent years, there has been increased interest in studying the relationship between celiac disease and female reproductive dysfunction, but the available data are contradictory. It is necessary to further study the prevalence and mechanisms of the disease pathogenesis, diagnostic capabilities and preventive measures for celiac disease in women with reproductive insufficiency.