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Zebrafish models of epigenetic regulation of CNS functions. / Лакстыгал, Антон Михайлович; de Abreu, Murilo S; Калуев, Алан Валерьевич.

In: Brain Research Bulletin, Vol. 142, 09.2018, p. 344-351.

Research output: Contribution to journal › Review article › peer-review

Harvard

Лакстыгал, АМ, de Abreu, MS & Калуев, АВ 2018, 'Zebrafish models of epigenetic regulation of CNS functions', Brain Research Bulletin, vol. 142, pp. 344-351. https://doi.org/10.1016/j.brainresbull.2018.08.022

APA

Лакстыгал, А. М., de Abreu, M. S., & Калуев, А. В. (2018). Zebrafish models of epigenetic regulation of CNS functions. Brain Research Bulletin, 142, 344-351. https://doi.org/10.1016/j.brainresbull.2018.08.022

Vancouver

Лакстыгал АМ, de Abreu MS, Калуев АВ. Zebrafish models of epigenetic regulation of CNS functions. Brain Research Bulletin. 2018 Sep;142:344-351. https://doi.org/10.1016/j.brainresbull.2018.08.022

Author

Лакстыгал, Антон Михайлович ; de Abreu, Murilo S ; Калуев, Алан Валерьевич. / Zebrafish models of epigenetic regulation of CNS functions. In: Brain Research Bulletin. 2018 ; Vol. 142. pp. 344-351.

BibTeX

@article{ddc1ab91c8354c33822058d50b97e302,
title = "Zebrafish models of epigenetic regulation of CNS functions",
abstract = "Epigenetic regulation has become a key focus of neuroscience and biopsychiatry, implicating DNA methylation, histone modification and other epigenetic mechanisms in various CNS disorders. Animal (experimental) models are a useful tool for epigenetic studies. Although most such research has been performed in rodents, the zebrafish (Danio rerio) is rapidly emerging as a new promising model organism in neuroscience. These fish are particularly suitable for genetic and epigenetic studies due to their fully sequenced genome, easiness of genetic analyses and high physiological and genetic homology with humans. Here, we discuss mounting evidence of epigenetic regulation of CNS functions in zebrafish, and outline future directions of translational research in this field.",
keywords = "Behavior, DNA methylation, Epigenetics, Histone modification, Translational psychiatry, Zebrafish",
author = "Лакстыгал, {Антон Михайлович} and {de Abreu}, {Murilo S} and Калуев, {Алан Валерьевич}",
note = "Funding Information: The research was supported by the Russian Foundation for Basic Research (RFBR) grant 16-04-00851 to АVK. The authors thank Mr. Andrey Volgin for his help with this manuscript.",
year = "2018",
month = sep,
doi = "10.1016/j.brainresbull.2018.08.022",
language = "English",
volume = "142",
pages = "344--351",
journal = "Brain Research Bulletin",
issn = "0361-9230",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Zebrafish models of epigenetic regulation of CNS functions

AU - Лакстыгал, Антон Михайлович

AU - de Abreu, Murilo S

AU - Калуев, Алан Валерьевич

N1 - Funding Information: The research was supported by the Russian Foundation for Basic Research (RFBR) grant 16-04-00851 to АVK. The authors thank Mr. Andrey Volgin for his help with this manuscript.

PY - 2018/9

Y1 - 2018/9

N2 - Epigenetic regulation has become a key focus of neuroscience and biopsychiatry, implicating DNA methylation, histone modification and other epigenetic mechanisms in various CNS disorders. Animal (experimental) models are a useful tool for epigenetic studies. Although most such research has been performed in rodents, the zebrafish (Danio rerio) is rapidly emerging as a new promising model organism in neuroscience. These fish are particularly suitable for genetic and epigenetic studies due to their fully sequenced genome, easiness of genetic analyses and high physiological and genetic homology with humans. Here, we discuss mounting evidence of epigenetic regulation of CNS functions in zebrafish, and outline future directions of translational research in this field.

AB - Epigenetic regulation has become a key focus of neuroscience and biopsychiatry, implicating DNA methylation, histone modification and other epigenetic mechanisms in various CNS disorders. Animal (experimental) models are a useful tool for epigenetic studies. Although most such research has been performed in rodents, the zebrafish (Danio rerio) is rapidly emerging as a new promising model organism in neuroscience. These fish are particularly suitable for genetic and epigenetic studies due to their fully sequenced genome, easiness of genetic analyses and high physiological and genetic homology with humans. Here, we discuss mounting evidence of epigenetic regulation of CNS functions in zebrafish, and outline future directions of translational research in this field.

KW - Behavior

KW - DNA methylation

KW - Epigenetics

KW - Histone modification

KW - Translational psychiatry

KW - Zebrafish

UR - http://www.scopus.com/inward/record.url?scp=85052754839&partnerID=8YFLogxK

U2 - 10.1016/j.brainresbull.2018.08.022

DO - 10.1016/j.brainresbull.2018.08.022

M3 - Review article

VL - 142

SP - 344

EP - 351

JO - Brain Research Bulletin

JF - Brain Research Bulletin

SN - 0361-9230

ER -

ID: 33901434