TY - JOUR

T1 - What is normal cognitive aging?

AU - Zalutskaya, N. M.

AU - Gomzyakova, N. A.

AU - Saraykin, D. M.

AU - Ananyeva, N. I.

AU - Neznanov, N. G.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Using the Addenbrooke's Cognitive Examination (ACE-III), the Stroop Test (ST), the Wechsler Memory Scale (WMS), and the Frontal Assessment Battery (FAB), we examined 44 respondents of an almost healthy «age norm» from 52 to 95 years old. Depending on age, the sample was divided into 2 groups, the first group included people under the age of 65 years (64 years old inclusive), the second group consisted of subjects over 65 years old. Statistically significant differences in the results of the survey of respondents of the two groups by the ACE-III were found in Memory and Total score indicators, while the level of cognitive functioning measured by the ACE-III decreased with age. The results of comparing the survey data using the Stroop Test indicate a decrease in the pace of work under load conditions and a weakening in the flexibility of organization of mental activity and concentration of attention, as well as increased interference in individuals of a more age group examined by us. Correlation analysis of the Stroop test data and the age of the examined showed cognitive control over information processing decreases, interfering influences increase, accuracy and pace of activity decrease, and the activity itself becomes more rigidas age increases. The results of the correlation analysis of the indicators of the WMS and age demonstrated a decrease in the level of mental control over activity, a deterioration of memory in the visual modality, and a progressive working memory reduction as age increases. With the growth of age, a decrease in frontal (executive) functions of healthy subjects, evaluated by the FAB, was found.

AB - Using the Addenbrooke's Cognitive Examination (ACE-III), the Stroop Test (ST), the Wechsler Memory Scale (WMS), and the Frontal Assessment Battery (FAB), we examined 44 respondents of an almost healthy «age norm» from 52 to 95 years old. Depending on age, the sample was divided into 2 groups, the first group included people under the age of 65 years (64 years old inclusive), the second group consisted of subjects over 65 years old. Statistically significant differences in the results of the survey of respondents of the two groups by the ACE-III were found in Memory and Total score indicators, while the level of cognitive functioning measured by the ACE-III decreased with age. The results of comparing the survey data using the Stroop Test indicate a decrease in the pace of work under load conditions and a weakening in the flexibility of organization of mental activity and concentration of attention, as well as increased interference in individuals of a more age group examined by us. Correlation analysis of the Stroop test data and the age of the examined showed cognitive control over information processing decreases, interfering influences increase, accuracy and pace of activity decrease, and the activity itself becomes more rigidas age increases. The results of the correlation analysis of the indicators of the WMS and age demonstrated a decrease in the level of mental control over activity, a deterioration of memory in the visual modality, and a progressive working memory reduction as age increases. With the growth of age, a decrease in frontal (executive) functions of healthy subjects, evaluated by the FAB, was found.

KW - Addenbrooke's cognitive scale

KW - cognitive functions

KW - Frontal Assessment Battery

KW - memory

KW - normal aging

KW - Stroop test

KW - Wechsler Memory Scale

UR - http://www.scopus.com/inward/record.url?scp=85103531916&partnerID=8YFLogxK

M3 - Article

C2 - 33774987

AN - SCOPUS:85103531916

VL - 33

SP - 1060

EP - 1068

JO - УСПЕХИ ГЕРОНТОЛОГИИ

JF - УСПЕХИ ГЕРОНТОЛОГИИ

SN - 1561-9125

IS - 6

ER -