Research output: Contribution to journal › Article › peer-review
Vzaimodeistvie molekuly DNK s koordinatsionnymi soedineniiami platiny i kobal'ta v rastvore. / Kas'ianenko, N. A.; Bogdanov, A. A.; Defrenne, C.
In: Biofizika, Vol. 47, No. 3, 2002, p. 449-452.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Vzaimodeistvie molekuly DNK s koordinatsionnymi soedineniiami platiny i kobal'ta v rastvore.
AU - Kas'ianenko, N. A.
AU - Bogdanov, A. A.
AU - Defrenne, C.
N1 - Copyright: This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2002
Y1 - 2002
N2 - The interaction of DNA with coordination compounds of divalent platinum and trivalent cobalt was studied. Complexes containing simultaneously different coordination compounds were prepared by various procedures. It was shown that the binding of trans-diaminodichloroplatinum (DDP) to DNA prevents its further complexing with cis-DDP, while in the presence of cis-DDP the possibility for trans-DDP to bind to DNA in solution remains. The study of similar DNA complexes with trans-DDP and cobalt hexamine indicated the competition for the binding sites of these compounds to the DNA molecule.
AB - The interaction of DNA with coordination compounds of divalent platinum and trivalent cobalt was studied. Complexes containing simultaneously different coordination compounds were prepared by various procedures. It was shown that the binding of trans-diaminodichloroplatinum (DDP) to DNA prevents its further complexing with cis-DDP, while in the presence of cis-DDP the possibility for trans-DDP to bind to DNA in solution remains. The study of similar DNA complexes with trans-DDP and cobalt hexamine indicated the competition for the binding sites of these compounds to the DNA molecule.
UR - http://www.scopus.com/inward/record.url?scp=0036561216&partnerID=8YFLogxK
M3 - статья
C2 - 12068600
AN - SCOPUS:0036561216
VL - 47
SP - 449
EP - 452
JO - БИОФИЗИКА
JF - БИОФИЗИКА
SN - 0006-3029
IS - 3
ER -
ID: 73392761