A study was made of the effect of the blood sera of persons of the control group and patients with various diseases of the blood on normal precursor cells of granulo-monocytopoiesis (CFU-GM) and leukemic clonogenic cells. A stimulating human blood serum effect on proliferation was noted during cultivation of normal CFU-GM and leukemic clonogenic cells in the "agar drop-liquid medium" system. As a rule, the stimulating serum effect manifested itself in the presence of feeder cells or a high "spontaneous" colony formation. Human blood sera can be added to a culture medium for improving its nutritive properties.

Translated title of the contributionEffect of the blood sera of patients with different pathologies on normal and leukemic cells--the precursors of granulo- and monocytopoiesis
Original languageRussian
Pages (from-to)93-96
Number of pages4
JournalTerapevticheskii Arkhiv
Volume58
Issue number12
StatePublished - 1986
Externally publishedYes

    Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

ID: 87442768