A study was made of the effect of the blood sera of persons of the control group and patients with various diseases of the blood on normal precursor cells of granulo-monocytopoiesis (CFU-GM) and leukemic clonogenic cells. A stimulating human blood serum effect on proliferation was noted during cultivation of normal CFU-GM and leukemic clonogenic cells in the "agar drop-liquid medium" system. As a rule, the stimulating serum effect manifested itself in the presence of feeder cells or a high "spontaneous" colony formation. Human blood sera can be added to a culture medium for improving its nutritive properties.
Translated title of the contribution | Effect of the blood sera of patients with different pathologies on normal and leukemic cells--the precursors of granulo- and monocytopoiesis |
---|---|
Original language | Russian |
Pages (from-to) | 93-96 |
Number of pages | 4 |
Journal | Terapevticheskii Arkhiv |
Volume | 58 |
Issue number | 12 |
State | Published - 1986 |
Externally published | Yes |
ID: 87442768