The influence of interruption of blood flow along the vena cava inferior on the indices of portohepatic and systemic hemodynamics was studied in 10 patients with a combined portal and caval hypertension and in 5 patients without such combinations. It was found that occlusion of the vena cava inferior was followed by some changes to the hemodynamic induces, their degree being dependent on the occlusion level and the diagnosed portal and caval hypertension. Patients with hepatic cirrhosis and symptoms of caval hypertension overcome the interruption of circulation along the vena cava inferior better than those without signs of portal and caval hypertension.