The bound and free GABA and glutamic acid content in the brain of F1 (CBA X C57B1/6) hybrid mice was investigated by the Eliott method. A tendency to a decrease of GABA and glutamate content in the brain with their practically constant bound/free ratio was observed 24 h after calcium-D-pantothenate injections (150 mumole/kg, 9 injections for 3 days). Calcium-D-homopantothenate injected in the same way caused a significant decrease in the GABA content, and a sharp drop of the bound/free GABA ratio. The effect is not associated with the influence of calcium ions in the composition of the injected compounds.

Translated title of the contributionEffect of vitamin B3-active compounds on the content of free and combined gamma-aminobutyric acid and glutamic acid in the brain of mice
Original languageRussian
Pages (from-to)671-673
Number of pages3
JournalUkrainskii biokhimicheskii zhurnal
Volume55
Issue number6
StatePublished - 1 Nov 1983

    Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

ID: 42771839