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Virusy grippa i ateroskleroz : rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii. / Pleskov, V M; Gurevich, V S; Pleskova, Iu V.

In: Vestnik Rossiiskoi Akademii Meditsinskikh Nauk, No. 4, 2003, p. 10-3.

Research output: Contribution to journal › Article › peer-review

Harvard

Pleskov, VM, Gurevich, VS & Pleskova, IV 2003, 'Virusy grippa i ateroskleroz: rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii', Vestnik Rossiiskoi Akademii Meditsinskikh Nauk, no. 4, pp. 10-3.

APA

Pleskov, V. M., Gurevich, V. S., & Pleskova, I. V. (2003). Virusy grippa i ateroskleroz: rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii. Vestnik Rossiiskoi Akademii Meditsinskikh Nauk, (4), 10-3.

Vancouver

Pleskov VM, Gurevich VS, Pleskova IV. Virusy grippa i ateroskleroz: rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii. Vestnik Rossiiskoi Akademii Meditsinskikh Nauk. 2003;(4):10-3.

Author

Pleskov, V M ; Gurevich, V S ; Pleskova, Iu V. / Virusy grippa i ateroskleroz : rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii. In: Vestnik Rossiiskoi Akademii Meditsinskikh Nauk. 2003 ; No. 4. pp. 10-3.

BibTeX

@article{8f59e675f77b49d0a96acd0f08881dd9,
title = "Virusy grippa i ateroskleroz: rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii",
abstract = "It was established that viral particles, like low-density lipoproteins (LDLP), when subjected to some modification changes, lost their ability to be internalized by tissue somatic cells and acquired tropism to macrophage cells. The data, obtained by us by using the polymerase chain reaction (PCR) method, made it possible to assert that atherosclerotic plaques, isolated from vessels of patients with ischemic heart disease (IHD) who underwent coronary bypass, contained RNA of the A(HINI) and AH3N3) influenza viruses. Whereas, the vessel portions, undamaged by atherosclerosis, did not contain any genetic substances of influenza viruses. It was for the first time that an experimentally supported understanding was expressed on that the atherosclerotic plaques serve as a {"}reservoir{"} for influenza viruses. It is also suggested that the mentioned plaques can be the carriers of influenza viruses for a long time, thus, prolonging the persistent form of influenza infection in the human body.",
keywords = "Aged, Animals, Arteriosclerosis/etiology, Coronary Artery Bypass, Coronary Artery Disease/virology, Coronary Vessels/virology, Humans, Influenza A virus/genetics, Influenza, Human/metabolism, Lipid Peroxidation, Lung/metabolism, Malondialdehyde/analysis, Mice, Middle Aged, Myocardial Ischemia/surgery, Polymerase Chain Reaction, RNA, Viral/analysis, Spectrophotometry, Thiobarbiturates, Time Factors, Tropism",
author = "Pleskov, {V M} and Gurevich, {V S} and Pleskova, {Iu V}",
year = "2003",
language = "русский",
pages = "10--3",
journal = "ВЕСТНИК РОССИЙСКОЙ АКАДЕМИИ МЕДИЦИНСКИХ НАУК",
issn = "0869-6047",
publisher = "Медицина",
number = "4",

}

RIS

TY - JOUR

T1 - Virusy grippa i ateroskleroz

T2 - rol' ateroskleroticheskikh bliashek v podderzhanii persistentnoĭ formy grippoznoĭ infektsii

AU - Pleskov, V M

AU - Gurevich, V S

AU - Pleskova, Iu V

PY - 2003

Y1 - 2003

N2 - It was established that viral particles, like low-density lipoproteins (LDLP), when subjected to some modification changes, lost their ability to be internalized by tissue somatic cells and acquired tropism to macrophage cells. The data, obtained by us by using the polymerase chain reaction (PCR) method, made it possible to assert that atherosclerotic plaques, isolated from vessels of patients with ischemic heart disease (IHD) who underwent coronary bypass, contained RNA of the A(HINI) and AH3N3) influenza viruses. Whereas, the vessel portions, undamaged by atherosclerosis, did not contain any genetic substances of influenza viruses. It was for the first time that an experimentally supported understanding was expressed on that the atherosclerotic plaques serve as a "reservoir" for influenza viruses. It is also suggested that the mentioned plaques can be the carriers of influenza viruses for a long time, thus, prolonging the persistent form of influenza infection in the human body.

AB - It was established that viral particles, like low-density lipoproteins (LDLP), when subjected to some modification changes, lost their ability to be internalized by tissue somatic cells and acquired tropism to macrophage cells. The data, obtained by us by using the polymerase chain reaction (PCR) method, made it possible to assert that atherosclerotic plaques, isolated from vessels of patients with ischemic heart disease (IHD) who underwent coronary bypass, contained RNA of the A(HINI) and AH3N3) influenza viruses. Whereas, the vessel portions, undamaged by atherosclerosis, did not contain any genetic substances of influenza viruses. It was for the first time that an experimentally supported understanding was expressed on that the atherosclerotic plaques serve as a "reservoir" for influenza viruses. It is also suggested that the mentioned plaques can be the carriers of influenza viruses for a long time, thus, prolonging the persistent form of influenza infection in the human body.

KW - Aged

KW - Animals

KW - Arteriosclerosis/etiology

KW - Coronary Artery Bypass

KW - Coronary Artery Disease/virology

KW - Coronary Vessels/virology

KW - Humans

KW - Influenza A virus/genetics

KW - Influenza, Human/metabolism

KW - Lipid Peroxidation

KW - Lung/metabolism

KW - Malondialdehyde/analysis

KW - Mice

KW - Middle Aged

KW - Myocardial Ischemia/surgery

KW - Polymerase Chain Reaction

KW - RNA, Viral/analysis

KW - Spectrophotometry

KW - Thiobarbiturates

KW - Time Factors

KW - Tropism

M3 - статья

C2 - 12741353

SP - 10

EP - 13

JO - ВЕСТНИК РОССИЙСКОЙ АКАДЕМИИ МЕДИЦИНСКИХ НАУК

JF - ВЕСТНИК РОССИЙСКОЙ АКАДЕМИИ МЕДИЦИНСКИХ НАУК

SN - 0869-6047

IS - 4

ER -

ID: 38738965