Abstract—: The ability of Lactobacillus plantarum strain 8RA-3 to secrete neurohormones arginine vasopressin and oxytocin when grown on solid and in liquid nutrient media was established. An increase in the concentration of secreted hormones was found to depend on duration of the cultivation of an L. plantarum 8PA-3 suspension culture. The ability to secrete oxytocin was poorly expressed in Escherichia coli M17 and Staphylococcus aureus K4 and was not found in Micrococcus luteus C6. The addition of these hormones and their receptor antagonists to the liquid nutrient medium did not affect the growth rate of L. plantarum 8PA-3 cells.