Abstract: NO₂ is a reactive gas which is produced mainly due to man-made activities (burning of fossil fuels) and influences negatively people organisms and environment. Since the Earth population keeps increasing, the content of the gas in the atmosphere is expected to rise. Satellite monitoring is the most optimal method to observe the spatio-temporal distribution of NO₂ in the troposphere globally which cannot be achieved by ground-based measurements. However, there are several different satellite measurement systems which provide the information on tropospheric NO₂. In the current study we compared tropospheric NO₂ data for the more than 10-year period retrieved from the measurements of OMI and GOME/SCIAMACHY/GOME-2 satellite measurement systems for the territories of Saint Petersburg and Leningrad region (Russia). Also, we investigated correlation between the NO₂ tropospheric content by satellite measurements and near-surface NO₂ concentration by ground-based measurements in Saint Petersburg. The research demonstrated that OMI and GOME/SCIAMACHY/GOME-2 data on tropospheric NO₂ content possessed large discrepancies (approximately 100% relative to OMI data) for the area and period of interest. The datasets did not correlate well but some similarities in a seasonal variation of the tropospheric NO₂ content for Saint Petersburg and Leningrad region were found. In addition, we registered an obvious correlation in the trend of near-surface and tropospheric NO₂ content obtained by ground-based and OMI satellite measurements respectively.