Understanding early-life pain and its effects on adult human and animal emotionality

Standard

Understanding early-life pain and its effects on adult human and animal emotionality : Translational lessons from rodent and zebrafish models. / de Abreu, Murilo S.; Giacomini, Ana C.V.V.; Genario, Rafael; Demin, Konstantin A.; Amstislavskaya, Tamara G.; Costa, Fabiano; Rosemberg, Denis B.; Sneddon, Lynne U.; Strekalova, Tatyana; Soares, Marta C.; Kalueff, Allan V.

In: Neuroscience Letters, Vol. 768, 136382, 18.01.2022.

Research output: Contribution to journal › Article

Author

de Abreu, Murilo S. ; Giacomini, Ana C.V.V. ; Genario, Rafael ; Demin, Konstantin A. ; Amstislavskaya, Tamara G. ; Costa, Fabiano ; Rosemberg, Denis B. ; Sneddon, Lynne U. ; Strekalova, Tatyana ; Soares, Marta C. ; Kalueff, Allan V. / Understanding early-life pain and its effects on adult human and animal emotionality : Translational lessons from rodent and zebrafish models. In: Neuroscience Letters. 2022 ; Vol. 768.

BibTeX

@article{ab72be1c75994a90be53c938d99a134b,

title = "Understanding early-life pain and its effects on adult human and animal emotionality: Translational lessons from rodent and zebrafish models",

abstract = "Critical for organismal survival, pain evokes strong physiological and behavioral responses in various sentient species. Clinical and preclinical (animal) studies markedly increase our understanding of biological consequences of developmental (early-life) adversity, as well as acute and chronic pain. However, the long-term effects of early-life pain exposure on human and animal emotional responses remain poorly understood. Here, we discuss experimental models of nociception in rodents and zebrafish, and summarize mounting evidence of the role of early-life pain in shaping emotional traits later in life. We also call for further development of animal models to probe the impact of early-life pain exposure on behavioral traits, brain disorders and novel therapeutic treatments.",

keywords = "Animal models, Behavior, Early-life exposure, Emotional response, Pain, LOW-BIRTH-WEIGHT, BEHAVIORAL-MODEL, CORTICOTROPIN-RELEASING-FACTOR, NEONATAL PAIN, RISK-FACTOR, CHILDREN BORN, CORTISOL-LEVELS, STRESS, INTERNALIZING BEHAVIORS, EXPOSURE",

author = "{de Abreu}, {Murilo S.} and Giacomini, {Ana C.V.V.} and Rafael Genario and Demin, {Konstantin A.} and Amstislavskaya, {Tamara G.} and Fabiano Costa and Rosemberg, {Denis B.} and Sneddon, {Lynne U.} and Tatyana Strekalova and Soares, {Marta C.} and Kalueff, {Allan V.}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier B.V.",

year = "2022",

month = jan,

day = "18",

doi = "10.1016/j.neulet.2021.136382",

language = "English",

volume = "768",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Understanding early-life pain and its effects on adult human and animal emotionality

T2 - Translational lessons from rodent and zebrafish models

AU - de Abreu, Murilo S.

AU - Giacomini, Ana C.V.V.

AU - Genario, Rafael

AU - Demin, Konstantin A.

AU - Amstislavskaya, Tamara G.

AU - Costa, Fabiano

AU - Rosemberg, Denis B.

AU - Sneddon, Lynne U.

AU - Strekalova, Tatyana

AU - Soares, Marta C.

AU - Kalueff, Allan V.

PY - 2022/1/18

Y1 - 2022/1/18

N2 - Critical for organismal survival, pain evokes strong physiological and behavioral responses in various sentient species. Clinical and preclinical (animal) studies markedly increase our understanding of biological consequences of developmental (early-life) adversity, as well as acute and chronic pain. However, the long-term effects of early-life pain exposure on human and animal emotional responses remain poorly understood. Here, we discuss experimental models of nociception in rodents and zebrafish, and summarize mounting evidence of the role of early-life pain in shaping emotional traits later in life. We also call for further development of animal models to probe the impact of early-life pain exposure on behavioral traits, brain disorders and novel therapeutic treatments.

AB - Critical for organismal survival, pain evokes strong physiological and behavioral responses in various sentient species. Clinical and preclinical (animal) studies markedly increase our understanding of biological consequences of developmental (early-life) adversity, as well as acute and chronic pain. However, the long-term effects of early-life pain exposure on human and animal emotional responses remain poorly understood. Here, we discuss experimental models of nociception in rodents and zebrafish, and summarize mounting evidence of the role of early-life pain in shaping emotional traits later in life. We also call for further development of animal models to probe the impact of early-life pain exposure on behavioral traits, brain disorders and novel therapeutic treatments.

KW - Animal models

KW - Behavior

KW - Early-life exposure

KW - Emotional response

KW - Pain

KW - LOW-BIRTH-WEIGHT

KW - BEHAVIORAL-MODEL

KW - CORTICOTROPIN-RELEASING-FACTOR

KW - NEONATAL PAIN

KW - RISK-FACTOR

KW - CHILDREN BORN

KW - CORTISOL-LEVELS

KW - STRESS

KW - INTERNALIZING BEHAVIORS

KW - EXPOSURE

UR - http://www.scopus.com/inward/record.url?scp=85120453374&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/fe7a94d7-2e27-38b7-920c-a18911b4ee61/

U2 - 10.1016/j.neulet.2021.136382

DO - 10.1016/j.neulet.2021.136382

M3 - Article

AN - SCOPUS:85120453374

VL - 768

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

M1 - 136382

ER -

ID: 89083648