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Understanding CNS effects of antimicrobial drugs using zebrafish models. / Kotova, Maria; Galstyan, David S. ; Kolesnikova, Tatiana O. ; de Abreu, Murilo; Amstislavskaya, Tamara; Strekalova, Tatyana ; Petersen, Elena; Yenkoyan, Konstantin; Demin, Konstantin A. ; Kalueff , Allan V. .

In: Veterinary Sciences, Vol. 10, No. 2, 96, 29.01.2023.

Research output: Contribution to journal › Review article › peer-review

Harvard

Kotova, M, Galstyan, DS, Kolesnikova, TO, de Abreu, M, Amstislavskaya, T, Strekalova, T, Petersen, E, Yenkoyan, K, Demin, KA & Kalueff , AV 2023, 'Understanding CNS effects of antimicrobial drugs using zebrafish models', Veterinary Sciences, vol. 10, no. 2, 96. https://doi.org/10.3390/vetsci10020096

APA

Kotova, M., Galstyan, D. S., Kolesnikova, T. O., de Abreu, M., Amstislavskaya, T., Strekalova, T., Petersen, E., Yenkoyan, K., Demin, K. A., & Kalueff , A. V. (2023). Understanding CNS effects of antimicrobial drugs using zebrafish models. Veterinary Sciences, 10(2), [96]. https://doi.org/10.3390/vetsci10020096

Vancouver

Kotova M, Galstyan DS, Kolesnikova TO, de Abreu M, Amstislavskaya T, Strekalova T et al. Understanding CNS effects of antimicrobial drugs using zebrafish models. Veterinary Sciences. 2023 Jan 29;10(2). 96. https://doi.org/10.3390/vetsci10020096

Author

Kotova, Maria ; Galstyan, David S. ; Kolesnikova, Tatiana O. ; de Abreu, Murilo ; Amstislavskaya, Tamara ; Strekalova, Tatyana ; Petersen, Elena ; Yenkoyan, Konstantin ; Demin, Konstantin A. ; Kalueff , Allan V. . / Understanding CNS effects of antimicrobial drugs using zebrafish models. In: Veterinary Sciences. 2023 ; Vol. 10, No. 2.

BibTeX

@article{a05d977bbf7547fd8e930903c6a1d081,
title = "Understanding CNS effects of antimicrobial drugs using zebrafish models",
abstract = "Antimicrobial drugs represent a diverse group of widely utilized antibiotic, antifungal, antiparasitic and antiviral agents. Their growing use and clinical importance necessitate our improved understanding of physiological effects of antimicrobial drugs, including their potential effects on the central nervous system (CNS), at molecular, cellular, and behavioral levels. In addition, antimicrobial drugs can alter the composition of gut microbiota, and hence affect the gut–microbiota–brain axis, further modulating brain and behavioral processes. Complementing rodent studies, the zebrafish (Danio rerio) emerges as a powerful model system for screening various antimicrobial drugs, including probing their putative CNS effects. Here, we critically discuss recent evidence on the effects of antimicrobial drugs on brain and behavior in zebrafish, and outline future related lines of research using this aquatic model organism.",
keywords = "antimicrobial drugs, microbiota, antibiotic, zebrafish, brain, behavior",
author = "Maria Kotova and Galstyan, {David S.} and Kolesnikova, {Tatiana O.} and {de Abreu}, Murilo and Tamara Amstislavskaya and Tatyana Strekalova and Elena Petersen and Konstantin Yenkoyan and Demin, {Konstantin A.} and Kalueff, {Allan V.}",
year = "2023",
month = jan,
day = "29",
doi = "10.3390/vetsci10020096",
language = "English",
volume = "10",
journal = "Veterinary Sciences",
issn = "2306-7381",
publisher = "MDPI AG",
number = "2",

}

RIS

TY - JOUR

T1 - Understanding CNS effects of antimicrobial drugs using zebrafish models

AU - Kotova, Maria

AU - Galstyan, David S.

AU - Kolesnikova, Tatiana O.

AU - de Abreu, Murilo

AU - Amstislavskaya, Tamara

AU - Strekalova, Tatyana

AU - Petersen, Elena

AU - Yenkoyan, Konstantin

AU - Demin, Konstantin A.

AU - Kalueff , Allan V.

PY - 2023/1/29

Y1 - 2023/1/29

N2 - Antimicrobial drugs represent a diverse group of widely utilized antibiotic, antifungal, antiparasitic and antiviral agents. Their growing use and clinical importance necessitate our improved understanding of physiological effects of antimicrobial drugs, including their potential effects on the central nervous system (CNS), at molecular, cellular, and behavioral levels. In addition, antimicrobial drugs can alter the composition of gut microbiota, and hence affect the gut–microbiota–brain axis, further modulating brain and behavioral processes. Complementing rodent studies, the zebrafish (Danio rerio) emerges as a powerful model system for screening various antimicrobial drugs, including probing their putative CNS effects. Here, we critically discuss recent evidence on the effects of antimicrobial drugs on brain and behavior in zebrafish, and outline future related lines of research using this aquatic model organism.

AB - Antimicrobial drugs represent a diverse group of widely utilized antibiotic, antifungal, antiparasitic and antiviral agents. Their growing use and clinical importance necessitate our improved understanding of physiological effects of antimicrobial drugs, including their potential effects on the central nervous system (CNS), at molecular, cellular, and behavioral levels. In addition, antimicrobial drugs can alter the composition of gut microbiota, and hence affect the gut–microbiota–brain axis, further modulating brain and behavioral processes. Complementing rodent studies, the zebrafish (Danio rerio) emerges as a powerful model system for screening various antimicrobial drugs, including probing their putative CNS effects. Here, we critically discuss recent evidence on the effects of antimicrobial drugs on brain and behavior in zebrafish, and outline future related lines of research using this aquatic model organism.

KW - antimicrobial drugs

KW - microbiota

KW - antibiotic

KW - zebrafish

KW - brain

KW - behavior

UR - https://www.mendeley.com/catalogue/285a3594-114c-3f8a-823a-c5d10d696685/

U2 - 10.3390/vetsci10020096

DO - 10.3390/vetsci10020096

M3 - Review article

C2 - 36851400

VL - 10

JO - Veterinary Sciences

JF - Veterinary Sciences

SN - 2306-7381

IS - 2

M1 - 96

ER -

ID: 102561692