Ugi reaction-derived 1H-pyrrol-2(5H)-ones proved as valid precursors to a new class of heterocyclic α-diazocarbonyl compounds

Research output: Contribution to journal › Article › peer-review

BM.5512.2019 Chemistry

Overview
Cite this

DOI

https://doi.org/10.1016/j.tetlet.2021.153598
Final published version

Anton Budeev
Grigory Kantin
Dmitry Dar'in
Mikhail Krasavin

1H-Pyrrol-2(5H)-ones synthesized via a modified literature procedure from primary amines, 3-substituted propiolic acids, isocyanides and glyoxal underwent a facile Regitz diazo transfer to give novel heterocyclic α-diazocarbonyl compounds – polysubstituted diazo pyrrol-2-ones.

Original language	English
Article number	153598
Journal	Tetrahedron Letters
DOIs	https://doi.org/10.1016/j.tetlet.2021.153598
State	E-pub ahead of print - 14 Dec 2021

Research areas

1H-pyrrol-2(5H)-ones, Diazo transfer reaction, Heterocyclic α-diazocarbonyl compounds, Isocyanides, Multicomponent reaction

Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

ID: 90454325