The recently introduced TruSeq synthetic long read (TSLR) technology generates long and accurate virtual reads from an assembly of barcoded pools of short reads. The TSLR method provides an attractive alternative to existing sequencing platforms that generate long but inaccurate reads. We describe the truSPAdes algorithm (http://bioinf.spbau.ru/spades) for TSLR assembly and show that it results in a dramatic improvement in the quality of metagenomics assemblies.
Original languageEnglish
Pages (from-to)248-250
JournalNature Methods
Volume13
DOIs
StatePublished - 2016
Externally publishedYes

    Research areas

  • DNA sequencing, Genome assembly algorithms, Software

ID: 7614546