Research output: Contribution to journal › Article › peer-review
The Vascular Impairment of Cognition Classification Consensus Study. / VICCCS group.
In: Alzheimer's and Dementia, Vol. 13, No. 6, 06.2017, p. 624-633.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The Vascular Impairment of Cognition Classification Consensus Study
AU - VICCCS group
AU - Skrobot, Olivia A.
AU - Love, Seth
AU - Kehoe, Patrick G.
AU - O'Brien, John
AU - Black, Sandra
AU - Chen, Christopher
AU - DeCarli, Charles
AU - Erkinjuntti, Timo
AU - Ford, Gary A.
AU - Kalaria, Rajesh N.
AU - Pantoni, Leonardo
AU - Pasquier, Florence
AU - Roman, Gustavo C.
AU - Wallin, Anders
AU - Sachdev, Perminder
AU - Kril, J.
AU - Skoog, Ingmar
AU - Ben-Shlomo, Yoav
AU - Passmore, Anthony P.
AU - Engelborghs, S.
AU - Lafosse, C.
AU - Bertolucci, P. H.
AU - Brucki, S.
AU - Caramelli, P.
AU - de Toledo Ferraz Alves, T. C.
AU - Bocti, C.
AU - Fulop, T.
AU - Hogan, D. B.
AU - Hsiung, G. R.
AU - Kirk, A.
AU - Leach, L.
AU - Robillard, A.
AU - Sahlas, D. J.
AU - Guo, Q.
AU - Tian, J.
AU - Hokkanen, L.
AU - Jokinen, H.
AU - Benisty, S.
AU - Deramecourt, V.
AU - Hauw, J.
AU - Lenoir, H.
AU - Tsatali, M.
AU - Tsolaki, M.
AU - Sundar, U.
AU - Coen, R. F.
AU - Korczyn, A. D.
AU - Altieri, M.
AU - Baldereschi, M.
AU - Caltagirone, C.
AU - Kruglov, L. S.
N1 - Funding Information: Declaration of interests: Prof. Ford reports personal fees from Pfizer, Athersys, AstraZeneca, Lundbeck, Cerevast, and Daiichi Sankyo and grants and personal fees from Boehringer Ingelheim, outside the submitted work. Prof. O'Brien reports personal fees from GE Healthcare, TauRx, and Cytox and grants and personal fees from Avid/Lilly, outside the submitted work. Prof. Skoog reports personal fees and other from Takeda, outside the submitted work. Outside the submitted work, Prof. Black reports institutional grants from Pfizer, GE Healthcare, Eli Lilly, Elan/Transition Therapeutics, Roche, and Cognoptix and personal fees from Pfizer, GE Healthcare, Eli Lilly, Eisai, Boehringer Ingelheim, and Novartis. Funding Information: This work was supported by a project grant (Ref117) from the Alzheimer's Society (UK). Publisher Copyright: © 2016 the Alzheimer's Association Copyright: Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2017/6
Y1 - 2017/6
N2 - Introduction Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment. Methods The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines. Results VICCCS had a mean of 122 (98–153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge. Discussion VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research.
AB - Introduction Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment. Methods The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines. Results VICCCS had a mean of 122 (98–153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge. Discussion VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research.
KW - Consensus
KW - Criteria
KW - Delphi
KW - Guidelines
KW - Vascular cognitive impairment
KW - Vascular dementia
UR - http://www.scopus.com/inward/record.url?scp=85013639675&partnerID=8YFLogxK
U2 - 10.1016/j.jalz.2016.10.007
DO - 10.1016/j.jalz.2016.10.007
M3 - Article
C2 - 27960092
AN - SCOPUS:85013639675
VL - 13
SP - 624
EP - 633
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
SN - 1552-5260
IS - 6
ER -
ID: 37620532