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@article{63313c7285714cf68f3bd5854890ef1a,
title = "The synthesis and study of carbonic anhydrase activity of sulfonamide-containing dibenzo[1,4]thiazepines",
abstract = "A one-pot synthesis approach to access sulfonamide-containing derivatives of dibenzo[1,4]thiazepine using primary amines and 2-[(2-nitro-4-sulfamoylphenyl)sulfanyl]benzoic acid as precursors was developed. The approach is based on a sequence of amidation steps and the subsequent tandem of the Smiles rearrangement and denitrocyclization reaction. The resulting tricyclic systems showed pronounced activity as inhibitors of bovine carbonic anhydrase isoform II.",
author = "Смирнова, {Дарья Сергеевна} and Шаройко, {Владимир Владимирович} and Калинин, {Станислав Алексеевич} and Сапегин, {Александр Владимирович}",
year = "2024",
month = jan,
day = "9",
doi = "10.1007/s10593-024-03279-2",
language = "English",
volume = "59",
pages = "833--838",
journal = "Chemistry of Heterocyclic Compounds",
issn = "0009-3122",
publisher = "Springer Nature",
number = "11-12",

}

RIS

TY - JOUR

T1 - The synthesis and study of carbonic anhydrase activity of sulfonamide-containing dibenzo[1,4]thiazepines

AU - Смирнова, Дарья Сергеевна

AU - Шаройко, Владимир Владимирович

AU - Калинин, Станислав Алексеевич

AU - Сапегин, Александр Владимирович

PY - 2024/1/9

Y1 - 2024/1/9

N2 - A one-pot synthesis approach to access sulfonamide-containing derivatives of dibenzo[1,4]thiazepine using primary amines and 2-[(2-nitro-4-sulfamoylphenyl)sulfanyl]benzoic acid as precursors was developed. The approach is based on a sequence of amidation steps and the subsequent tandem of the Smiles rearrangement and denitrocyclization reaction. The resulting tricyclic systems showed pronounced activity as inhibitors of bovine carbonic anhydrase isoform II.

AB - A one-pot synthesis approach to access sulfonamide-containing derivatives of dibenzo[1,4]thiazepine using primary amines and 2-[(2-nitro-4-sulfamoylphenyl)sulfanyl]benzoic acid as precursors was developed. The approach is based on a sequence of amidation steps and the subsequent tandem of the Smiles rearrangement and denitrocyclization reaction. The resulting tricyclic systems showed pronounced activity as inhibitors of bovine carbonic anhydrase isoform II.

UR - https://www.mendeley.com/catalogue/037eaa38-650b-3d22-9604-f3a7ad82db23/

U2 - 10.1007/s10593-024-03279-2

DO - 10.1007/s10593-024-03279-2

M3 - Article

VL - 59

SP - 833

EP - 838

JO - Chemistry of Heterocyclic Compounds

JF - Chemistry of Heterocyclic Compounds

SN - 0009-3122

IS - 11-12

ER -

ID: 115629937