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The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity. / Kravtsova, V. V. ; Saburova, E. A. ; Krivoi, I. I. .

In: Biophysics (Russian Federation), Vol. 64, No. 5, 12.2019, p. 772–776.

Research output: Contribution to journal › Article › peer-review

Harvard

Kravtsova, VV, Saburova, EA & Krivoi, II 2019, 'The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity', Biophysics (Russian Federation), vol. 64, no. 5, pp. 772–776. https://doi.org/10.1134/S0006350919050129

APA

Kravtsova, V. V., Saburova, E. A., & Krivoi, I. I. (2019). The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity. Biophysics (Russian Federation), 64(5), 772–776. https://doi.org/10.1134/S0006350919050129

Vancouver

Kravtsova VV, Saburova EA, Krivoi II. The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity. Biophysics (Russian Federation). 2019 Dec;64(5):772–776. https://doi.org/10.1134/S0006350919050129

Author

Kravtsova, V. V. ; Saburova, E. A. ; Krivoi, I. I. . / The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity. In: Biophysics (Russian Federation). 2019 ; Vol. 64, No. 5. pp. 772–776.

BibTeX

@article{4ba3f5e28cff4721898e24f548abe1ec,
title = "The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity",
abstract = "In this study we analyzed the distribution of nicotinic acetylcholine receptors, the degree of their fragmentation, endplate area, and membrane localization of the α2 isoform of the Na,K–ATPase in the rat soleus muscle after functional unloading (via the method of hindlimb suspension) for 1–3 days. After unloading increased endplate fragmentation accompanied by a decrease in the area of individual fragments was observed; the total area of the endplates did not change. The density of distribution of nicotinic acetylcholine receptors also remained unaltered; however, the density of the distribution of the α2 isoform of the Na,K– ATPase significantly decreased. Presumably, these changes resulted from adaptive skeletal muscle remodeling, which develops not only during chronic disorders, but even in the early stages of motor dysfunction.",
keywords = "motor endplate, nicotinic acetylcholine receptor, Na,K-ATPase isoforms, motor activity, motor endplate, nicotinic acetylcholine receptor, Na, K-ATPase isoforms, motor activity",
author = "Kravtsova, {V. V.} and Saburova, {E. A.} and Krivoi, {I. I.}",
note = "Kravtsova, V.V., Saburova, E.A. & Krivoi, I.I. The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity. BIOPHYSICS 64, 772–776 (2019) doi:10.1134/S0006350919050129",
year = "2019",
month = dec,
doi = "10.1134/S0006350919050129",
language = "English",
volume = "64",
pages = "772–776",
journal = "Biophysics (Russian Federation)",
issn = "0006-3509",
publisher = "Springer Nature",
number = "5",

}

RIS

TY - JOUR

T1 - The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity

AU - Kravtsova, V. V.

AU - Saburova, E. A.

AU - Krivoi, I. I.

N1 - Kravtsova, V.V., Saburova, E.A. & Krivoi, I.I. The Structural and Functional Characteristics of Rat Soleus Endplates under Short-Term Disruption of Motor Activity. BIOPHYSICS 64, 772–776 (2019) doi:10.1134/S0006350919050129

PY - 2019/12

Y1 - 2019/12

N2 - In this study we analyzed the distribution of nicotinic acetylcholine receptors, the degree of their fragmentation, endplate area, and membrane localization of the α2 isoform of the Na,K–ATPase in the rat soleus muscle after functional unloading (via the method of hindlimb suspension) for 1–3 days. After unloading increased endplate fragmentation accompanied by a decrease in the area of individual fragments was observed; the total area of the endplates did not change. The density of distribution of nicotinic acetylcholine receptors also remained unaltered; however, the density of the distribution of the α2 isoform of the Na,K– ATPase significantly decreased. Presumably, these changes resulted from adaptive skeletal muscle remodeling, which develops not only during chronic disorders, but even in the early stages of motor dysfunction.

AB - In this study we analyzed the distribution of nicotinic acetylcholine receptors, the degree of their fragmentation, endplate area, and membrane localization of the α2 isoform of the Na,K–ATPase in the rat soleus muscle after functional unloading (via the method of hindlimb suspension) for 1–3 days. After unloading increased endplate fragmentation accompanied by a decrease in the area of individual fragments was observed; the total area of the endplates did not change. The density of distribution of nicotinic acetylcholine receptors also remained unaltered; however, the density of the distribution of the α2 isoform of the Na,K– ATPase significantly decreased. Presumably, these changes resulted from adaptive skeletal muscle remodeling, which develops not only during chronic disorders, but even in the early stages of motor dysfunction.

KW - motor endplate, nicotinic acetylcholine receptor, Na,K-ATPase isoforms, motor activity

KW - motor endplate

KW - nicotinic acetylcholine receptor

KW - Na

KW - K-ATPase isoforms

KW - motor activity

UR - http://www.scopus.com/inward/record.url?scp=85076485835&partnerID=8YFLogxK

U2 - 10.1134/S0006350919050129

DO - 10.1134/S0006350919050129

M3 - Article

VL - 64

SP - 772

EP - 776

JO - Biophysics (Russian Federation)

JF - Biophysics (Russian Federation)

SN - 0006-3509

IS - 5

ER -

ID: 49040194