Research output: Contribution to journal › Article › peer-review
The stability of chromosomes in yeast. / Larionov, V. L.; Karpova, T. S.; Zhouravleva, G. A.; Pashina, O. B.; Nikolaishvili, N. T.; Kouprina, N. Y.
In: Current Genetics, Vol. 11, No. 6-7, 03.1987, p. 435-443.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The stability of chromosomes in yeast
AU - Larionov, V. L.
AU - Karpova, T. S.
AU - Zhouravleva, G. A.
AU - Pashina, O. B.
AU - Nikolaishvili, N. T.
AU - Kouprina, N. Y.
PY - 1987/3
Y1 - 1987/3
N2 - CL mutants with high instability of chromosome III were UV-induced in haploid strain disomic for chromosome III. The obtained CL mutants can be divided into two groups: (1) CL2, CL3, CL7, CL11-L13 with elevated level of spontaneous inter- and intragenic recombination and (2) CL4, CL8 in which instability of chromosome III is not accompanied by elevation of mitotic recombination frequency. CL4 and CL8 mutants also show unstable maintenance of artificial minichromosomes with different chromosomal replicators and centromeric loci. The instability of chromosome III and minichromosomes in CL4 and CL8 is determined by two nonallelic genes designated ch14 and ch18. The role of ch14 and ch18 genes in mitotic chromosome transmission is discussed.
AB - CL mutants with high instability of chromosome III were UV-induced in haploid strain disomic for chromosome III. The obtained CL mutants can be divided into two groups: (1) CL2, CL3, CL7, CL11-L13 with elevated level of spontaneous inter- and intragenic recombination and (2) CL4, CL8 in which instability of chromosome III is not accompanied by elevation of mitotic recombination frequency. CL4 and CL8 mutants also show unstable maintenance of artificial minichromosomes with different chromosomal replicators and centromeric loci. The instability of chromosome III and minichromosomes in CL4 and CL8 is determined by two nonallelic genes designated ch14 and ch18. The role of ch14 and ch18 genes in mitotic chromosome transmission is discussed.
KW - Centromere-containing plasmids
KW - charomyces cerevisiae
KW - Mitotic stability of chromosomes and minichromosomes
KW - Yeast transformation
UR - http://www.scopus.com/inward/record.url?scp=0023106721&partnerID=8YFLogxK
U2 - 10.1007/BF00384604
DO - 10.1007/BF00384604
M3 - Article
C2 - 2836079
AN - SCOPUS:0023106721
VL - 11
SP - 435
EP - 443
JO - Current Genetics
JF - Current Genetics
SN - 0172-8083
IS - 6-7
ER -
ID: 84959034