This paper investigates the situation in the sphere of donor blood circulation. The main problems and the trends in this sphere are reviewed. In order to analyze the state regulation the measures of social support of donors are identified. A survey of donors on the basis of the Blood Center of the Belgorod region was conducted, as well as an interview with the chief doctor of the Center. A social portrait of a donor is compiled. Based on the research results, recommendations for improving the activities of the blood service are provided.